Transcranial alternating current stimulation (tACS) for Working Memory

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Minnesota, Minneapolis, MN
Working Memory
Transcranial alternating current stimulation (tACS) - Device
Eligibility
18 - 65
All Sexes
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Study Summary

This trial will test if a brain stimulation technique can improve working memory in adults. Transcranial alternating current stimulation (tACS) is a treatment that is used to improve Working Memory. This treatment has previously been approved by the FDA for a different condition. In this clinical trial, patients will not receive a placebo.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 2 Secondary · Reporting Duration: Five minutes post-stimulation

Five minutes post-stimulation
Changes in electroencephalographic (EEG) connectivity
Immediate effect during stimulation
Changes in reaction time
Changes in working memory performance

Trial Safety

Trial Design

4 Treatment Groups

Frontoparietal Slow Theta Stimulation
1 of 4
Frontoparietal Fast Theta Stimulation
1 of 4
Parietofrontal Fast Theta Stimulation
1 of 4
Parietofrontal Slow Theta Stimulation
1 of 4
Experimental Treatment

24 Total Participants · 4 Treatment Groups

Primary Treatment: Transcranial alternating current stimulation (tACS) · No Placebo Group · N/A

Frontoparietal Slow Theta Stimulation
Device
Experimental Group · 1 Intervention: Transcranial alternating current stimulation (tACS) · Intervention Types: Device
Frontoparietal Fast Theta Stimulation
Device
Experimental Group · 1 Intervention: Transcranial alternating current stimulation (tACS) · Intervention Types: Device
Parietofrontal Fast Theta Stimulation
Device
Experimental Group · 1 Intervention: Transcranial alternating current stimulation (tACS) · Intervention Types: Device
Parietofrontal Slow Theta Stimulation
Device
Experimental Group · 1 Intervention: Transcranial alternating current stimulation (tACS) · Intervention Types: Device

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: five minutes post-stimulation
Closest Location: University of Minnesota · Minneapolis, MN
Photo of University of Minnesota  1Photo of University of Minnesota  2Photo of University of Minnesota 3
1993First Recorded Clinical Trial
2 TrialsResearching Working Memory
833 CompletedClinical Trials

Who is running the clinical trial?

University of MinnesotaLead Sponsor
1,229 Previous Clinical Trials
1,455,108 Total Patients Enrolled
1 Trials studying Working Memory
16 Patients Enrolled for Working Memory
Brain & Behavior Research FoundationOTHER
54 Previous Clinical Trials
2,568 Total Patients Enrolled
Ivan Alekseichuk, PhDPrincipal InvestigatorUniversity of Minnesota

Eligibility Criteria

Age 18 - 65 · All Participants · 2 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are eligible for the study if you are between the ages of 18 and 45 years old.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.