570 Participants Needed

Brain Stimulation for Age-Related Memory Decline

RM
Overseen ByRobert M. G. Reinhart, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Boston University Charles River Campus
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Approved in 2 JurisdictionsThis treatment is already approved in other countries

Trial Summary

What is the purpose of this trial?

The research program will evaluate the theoretical claim that age-related memory and cognitive decline in humans result from the inefficient orchestration of rhythmic activity within large-scale cortical networks. The results will contribute to the basic science groundwork for developing future non-pharmacological interventions aimed at boosting memory and cognition in aging and clinical populations.

Eligibility Criteria

This trial is for older adults aged 68-80 with normal cognitive function (as shown by specific mental exams), no psychoactive medication use, and good vision. They must not have electronic implants, metal in the head, skin sensitivity issues, depression, neurological problems or a history of head injury.

Inclusion Criteria

I have never had a head injury or neurological problems.
Must have no metal implants in head
Must have no claustrophobia
See 8 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive noninvasive transcranial electrical current stimulation while performing computer-based tasks to assess memory and cognitive function

6-8 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

  • High definition transcranial electrical current stimulation
Trial Overview The study tests if high definition transcranial electrical current stimulation can improve memory and cognition in older adults by enhancing brain activity patterns. It's non-drug based and could lead to new treatments for age-related cognitive decline.
Participant Groups
2Treatment groups
Experimental Treatment
Placebo Group
Group I: active stimulationExperimental Treatment1 Intervention
Group II: sham stimulationPlacebo Group1 Intervention

High definition transcranial electrical current stimulation is already approved in United States, European Union for the following indications:

🇺🇸
Approved in United States as High-definition transcranial direct current stimulation for:
  • Investigational use for Alzheimer's disease-related memory impairment
🇪🇺
Approved in European Union as High-definition transcranial direct current stimulation for:
  • Investigational use for Alzheimer's disease-related memory impairment

Find a Clinic Near You

Who Is Running the Clinical Trial?

Boston University Charles River Campus

Lead Sponsor

Trials
125
Recruited
14,100+
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