Virtual Reality for Cognitive Impairment
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if combining virtual reality (VR) with physical activity can boost brain health in older adults. Researchers will divide participants into three groups: one will engage in physical activities like cycling, another will participate in VR-based cognitive games, and the third will combine both activities. The trial lasts 16 weeks and examines the impact of these activities on brain and physical health. Suitable candidates include English speakers aged 50 to 85 who can safely ride a stationary bike. As an unphased trial, this study provides participants with a unique opportunity to contribute to innovative research that could enhance brain health strategies for older adults.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team or your doctor.
What prior data suggests that this virtual reality intervention is safe for cognitive impairment?
Research shows that older adults generally handle virtual reality (VR) cognitive training well. Studies have examined its usability and found that only a few people report mild dizziness or nausea, known as VR sickness. Importantly, VR is a promising tool to boost motivation and improve thinking and memory skills.
For activities that combine physical and mental exercises using VR, evidence shows these can enhance thinking skills in older adults with memory problems. The data suggest that participants usually experience improvements without major negative effects, indicating the treatment is safe and typically harmless.
Overall, previous studies have shown that the treatments tested in this trial are safe and beneficial, with few negative effects reported. Participants generally manage these activities well, making them a promising option for improving brain health.12345Why are researchers excited about this trial?
Researchers are excited about using virtual reality (VR) for cognitive impairment because it offers an innovative way to enhance both physical and mental activities simultaneously. Unlike traditional methods like medication or standard physical exercises, this approach combines physical cycling with a VR spatial navigation game, potentially boosting brain function more effectively. The VR aspect uniquely engages users by simulating real-world navigation tasks, which may help improve memory and cognitive skills in a more immersive and interactive way. This dual activity could lead to better overall cognitive improvements compared to traditional single-focus treatments.
What evidence suggests that this trial's treatments could be effective for cognitive impairment?
Research has shown that virtual reality (VR) activities can enhance memory and thinking skills in older adults, particularly those with memory problems. Studies have found that fully immersive VR training can boost overall brain function in individuals with mild memory issues. In this trial, participants may engage in various activities.
One group will participate in VR activities that combine physical exercise and mental challenges, which have strong evidence of significantly improving thinking skills. These combined activities have improved attention, mental abilities, and quality of life for those with memory difficulties.
Another group will focus on physical activities, like cycling, known to support brain health by increasing blood flow and stimulating brain activity, helping to maintain or improve thinking skills.
A third group will engage in cognitive activities using VR spatial navigation only. Overall, combining physical and mental challenges through VR appears promising for improving brain health in older adults.13567Are You a Good Fit for This Trial?
This trial is for English-speaking adults aged 50-85 who can safely ride a stationary bike. It's not suitable for those with dementia, severe sensory deficits, neurological disorders, or an inability to cycle safely. People with MRI contraindications like pacemakers or a fear of needles/blood are also excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants engage in one of three interventions: physical activity, VR cognitive activity, or combined VR physical and cognitive activity to improve brain health and cognition
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Cognitive Activity (VR)
- Physical Activity
- Physical and Cognitive Activity
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, San Diego
Lead Sponsor