High-Protein, Low-Glycemic Diet for Metabolic Syndrome
(MAPS Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how a high-protein, low-glycemic diet, including regular potato consumption, might benefit people with Metabolic Syndrome. Metabolic Syndrome consists of conditions like high blood pressure, high blood sugar, and excess body fat around the waist, which increase the risk of heart disease, stroke, and diabetes. Participants will follow different meal plans for 16 weeks to determine if regular potato consumption can improve their health. Individuals with Metabolic Syndrome who frequently consume high-sugar foods may be well-suited for this study. As an unphased trial, this study provides a unique opportunity to enhance understanding of dietary impacts on Metabolic Syndrome.
Will I have to stop taking my current medications?
The trial excludes participants who are on prescription medications related to heart disease or type 2 diabetes, so you may need to stop these medications to participate.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research has shown that including potatoes in a high-protein diet does not harm health markers in people with Metabolic Syndrome. One study found that white potatoes do not negatively affect blood sugar, cholesterol, or blood pressure compared to white rice and even slightly aid in weight management.
Another study examined processed potatoes and found similar results, suggesting that eating potatoes may be safe for those with Metabolic Syndrome. However, some research indicates that replacing potatoes with whole grains might slightly reduce the risk of diabetes.
The effects of high-protein diets can vary. Some people experience benefits, while others notice no change or even negative effects. Overall, eating potatoes as part of a high-protein, low-sugar diet appears to be generally well-tolerated.
In summary, current research suggests that adding potatoes, whether fresh or processed, to a diet like the one being tested should be safe for most people.12345Why are researchers excited about this trial?
Unlike traditional treatments for metabolic syndrome that often focus on medication and lifestyle changes such as increased exercise and reduced caloric intake, this approach uses a dietary intervention with a higher protein, low-glycemic load diet that includes different forms of potatoes. Researchers are excited because this method may provide an alternative way to manage blood sugar levels and weight through specific dietary choices rather than medication alone. The inclusion of white potatoes and processed potato products in the diet presents a new way to maintain low glycemic impact while potentially improving nutritional satisfaction and adherence to dietary changes. By focusing on the types of carbohydrates consumed, this approach could offer a more sustainable and enjoyable way to manage metabolic syndrome.
What evidence suggests that this trial's treatments could be effective for Metabolic Syndrome?
This trial will compare different versions of a high-protein, low-glycemic diet for individuals with Metabolic Syndrome (MetS). Studies have shown that a diet high in protein and low in foods that quickly raise blood sugar benefits MetS. For example, eating white potatoes instead of white rice did not raise blood sugar levels and even aided in slight weight loss. Other research indicates that diets with slowly digested potatoes can help reduce signs of inflammation. However, some studies suggest that replacing potatoes with whole grains might lower the risk of developing type 2 diabetes by about 8%. Overall, potatoes can be part of a healthy diet for MetS when included in a balanced meal plan that doesn't spike blood sugar. Participants in this trial will follow one of the specific diet plans being tested, which include variations with control carbohydrates, white potatoes, or processed potatoes.34678
Are You a Good Fit for This Trial?
Adults over 18 with Metabolic Syndrome, characterized by a combination of high triglycerides, low HDL cholesterol, high blood pressure, elevated fasting glucose levels or abdominal obesity. Participants should be from Northwest Arkansas and currently eating a diet high in glycemic load. Those on heart disease or diabetes medications, with needle phobia, food allergies or dietary restrictions like vegetarianism are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants consume low- to moderate-glycemic load meals for 16 weeks, with specific dietary interventions based on trial arm
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Higher protein, low glycemic load diet
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Arkansas, Fayetteville
Lead Sponsor