Headache Clinical Trials 2022

Browse 95 Headache Medical Studies Across 131 Cities

16 Phase 3 Trial · 291 Headache Clinics

Reviewed by Michael Gill, B. Sc.
Photo of NYU Langone Health 1
Phase-Based Progress Estimates
1
Effectiveness
1
Safety

Smartphone-Based Progressive Muscle Relaxation Therapy (PMR)for Migraine

New York, NY
18+
All Sexes
The goal of this research is to assess the utility of smartphone-based progressive muscle relaxation (PMR) for the treatment of migraine and sleep. While there are many commercially available electronic diary and mind-body intervention apps for headache, there is little data showing their efficacy. RELAXaHEAD app incorporates the electronic PMR that was successfully used in an earlier epilepsy study and beta tested with headache specialist and migraine patient input. It also is an electric headache diary. The app has been studied and findings have been reported in multiple peer reviewed publications. Also, the app has been updated based on prior feedback from the studies. Now, this 2-arm randomized controlled study will evaluate the feasibility and acceptability of RELAXaHEAD for use with patients with migraine and comorbid insomnia. . One arm will be the RELAX group (the RELAXaHEAD app) and the other arm will be a monitored usual care (MUC) group (this group receives standard of care and uses the electronic daily symptom reporting diary). The goals are to assess the feasibility and adherence of the RELAX intervention in persons with migraine and insomnia (Aim 1) and to gather exploratory data on the effects of the RELAX intervention on headache and sleep related outcome measures (Aim 2).
Recruiting
Has No Placebo
Photo of pennsylvania 1
Phase-Based Progress Estimates
1
Effectiveness
1
Safety

CarePathfor Headache

Danville, PA
18+
All Sexes
Between January 2020 to August 2021, fifty percent of patients referred from Geisinger's primary care sites to Neurology for headaches did not trial appropriate first line therapy prior to referral, and there was limited access available at Geisinger's Neurology department. This project was initiated to improve patient experience, management of headache, and provider experience as it relates to headache management. Geisinger's Neurology department, pharmacy department, and Community Medicine Service Line (CMSL) sites have collaborated to develop a Headache CarePath (i.e., a best practice alert containing: an EPIC headache assessment, Express Lane for prescriptions, and Ask-a-doc button for Neurology consult) and piloted at 2 CMSL sites (Woodbine, Selinsgrove) to gain some initial feedback. The feedback has been incorporated into best practice alert (BPA) language and criteria. The project team now plans to implement this CarePath to half of CMSL sites first while the other half of CMSL sites will continue to practice the standard of care as of today. The team will evaluate the impact of this CarePath on patient outcomes [change in Headache Impact Test-6 (HIT-6) scores, change in the frequency of headaches, and change in pain intensity], emergency department (ED) visits, number of referrals to Neurology for headache, and prescribing of headache medications by comparing the measures in clinics that had the CarePath implemented to those that did not. Patient outcomes will be collected by Geisinger's Survey Core, which will reach out telephonically to patients to ask about the status of their headaches (HIT-6, frequency, intensity of headaches, M-TOQ-5). Other measures will be collected and analyzed using secondary data sources such as electronic health record (EHR) data. The initial implementation is planned for 6-9 months. The findings from this evaluation will help the CarePath team identify any remaining opportunities or guide the direction of its future enhancements of the CarePath tools. The results of this evaluation will be shared with the Geisinger leadership to demonstrate its value to the organization.
Waitlist Available
Has No Placebo
25 Headache Clinical Trials Near Me
New York, NY
Rochester, MN
Youngstown, OH
Stanford, CA
More Trial Locations
An interactive map to display trial locations for NYU Langone Health, Mayo Clinic in Rochester, Youngstown State University, Stanford University, and 24 more locations.
Most Popular References for Headache Clinical Trials
Frequency
Citation
Top Hospitals for Headache Clinical Trials
Location
Active Headache Clinical Trials
All Time Trials for Headache
First Recorded Headache Trial
Trials
New England Institute for Clinical Research, Stamford, Connecticut
3
7
2012
Top Treatments for Headache Clinical Trials
Treatment Name
Active Headache Clinical Trials
All Time Trials for Headache
First Recorded Headache Trial
Trials
Smartphone-Based Progressive Muscle Relaxation Therapy (PMR)
1
1
2022
vagal nerve stimulator
1
1
2022
Top Cities for Headache Clinical Trials
City
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Seattle, Washington
8
Seattle Children's Hospital Research Foundation
Pittsburgh, Pennsylvania
7
UPMC Children's Hospital of Pittsburgh
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About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 28th, 2021

Last Reviewed: September 8th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.