← Back to Search

Procedure

Modified Lumbar Puncture for Spinal Tap Headache

N/A

Waitlist Available

Led By Jay-Jiguang Zhu, MD,PhD

Research Sponsored by The University of Texas Health Science Center, Houston

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Participants with Karnofsky Performance Scale (KPS) ≥ 60

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 5 days after the lp

Awards & highlights

Study Summary

This trial studies if a modified procedure reduces the risk of PLPH and epidural blood patch (EBP) usage. Factors affecting risk are also identified.

Who is the study for?

This trial is for individuals who need a lumbar puncture (LP) for diagnostic or therapeutic reasons, can consent to the study, will follow all procedures, and have a Karnofsky Performance Scale score of 60 or above. It excludes those on certain blood thinners unless stopped as per guidelines, with chronic or acute headaches, recent neurosurgical implants, multiple dural punctures in one LP session, coagulopathy issues, procedural complications requiring needle changes, suspected high brain pressure or severe spinal deformities.Check my eligibility

What is being tested?

The study tests whether a modified LP procedure can lower the occurrence of post-lumbar puncture headaches to 5% or less and reduce the need for epidural blood patch treatments to below 10% among those affected. It also aims to identify factors influencing these headaches' incidence.See study design

What are the potential side effects?

While not explicitly stated in this summary information provided about side effects from the modified LP procedure itself; typically an LP may cause potential side effects such as back pain at the needle insertion site, minor bleeding into the skin around it and sometimes temporary numbness in your legs.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I can care for myself but may need occasional help.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 5 days after lp

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~5 days after lp

This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 days after lp for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Number of participants with headaches as assessed by a questionnaire

Secondary outcome measures

Number of participants that use the epidural blood patch

Trial Design

1Treatment groups

Experimental Treatment

Group I: Modified Lumbar PunctureExperimental Treatment1 Intervention

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

The University of Texas Health Science Center, HoustonLead Sponsor

904 Previous Clinical Trials

320,897 Total Patients Enrolled

1 Trials studying Post-Lumbar Puncture Headache

Jay-Jiguang Zhu, MD,PhDPrincipal InvestigatorThe University of Texas Health Science Center, Houston

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this experimental study presently open to new participants?

"This clinical trial, which was first posted in October 20th 2023 and updated last on September 25th 2023, is not presently enrolling patients. However, 891 other trials are actively seeking participants at this time."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

A Prospective Study of a Modified Lumbar Puncture (LP) Procedure That Reduces Post-Lumbar Puncture Headaches (PLPH) in Patients

Jay-Jiguang Zhu 2023. "A Prospective Study of a Modified Lumbar Puncture (LP) Procedure That Reduces Post-Lumbar Puncture Headaches (PLPH) in Patients". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06062446.

All > Headache