Diabetes Prevention Program for Obesity

(SCULPT-Job Trial)

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of California, San Francisco

Disqualifiers: Pregnancy, Diabetes, Myocardial infarction, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 12 months

15 Participants Needed

Trial Summary

What is the purpose of this trial?

This is an research study about clinical, psychosocial, and behavioral factors that impact weight loss, weight maintenance, and cardiovascular disease in socially disadvantaged persons.

Research Team

Michelle A Albert, MD

Principal Investigator

University of California, SF

Eligibility Criteria

The SCULPT-Job Cohort Study is for adults over 18 with a BMI above 25 (or above 22 for Asian ethnicity), from various socioeconomic backgrounds. It's not for those with certain cognitive conditions, active housing issues, recent mothers, recent orthopedic surgery patients, non-speakers of English/Spanish/Chinese, or people with diabetes or recent severe heart problems.

Inclusion Criteria

BMI > 25 kg/m2 (for Asian ethnicity BMI > 22 kg/m2)

Includes participants from socioeconomically diverse backgrounds

I am older than 18 years.

Exclusion Criteria

History of physician diagnosed cognitive, developmental or psychiatric conditions

Persons facing housing eviction or undergoing an active housing leasing process (e.g getting their credit report in shape for a potential lease, in the process of getting a new housing lease)

Pregnancy or post-partum state (< 12 months post-partum)

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo the Diabetes Prevention Program (DPP) for weight loss and cardiovascular health improvement

12 months

Regular visits as per DPP schedule

Maintenance

Participants are monitored for BMI maintenance and cardiovascular health

6 months

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

• Diabetes Prevention Program

Trial Overview This study tests the Diabetes Prevention Program to see how it affects weight loss and maintenance as well as cardiovascular health in socially disadvantaged individuals. The focus is on clinical outcomes alongside psychosocial and behavioral factors.

Participant Groups

Group I: Diabetes Prevention Program Experimental Treatment 1 Intervention

The DPP is a behavioral obesity and diabetes prevention program run by the YMCA, over a 12-month period.

Who Is Running the Clinical Trial?

University of California, San Francisco

Lead Sponsor

Trials

2,636

Recruited

19,080,000+

American Heart Association

Collaborator

Trials

352

Recruited

6,196,000+