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Exparel for Craniofacial Pain
Study Summary
This trial will test whether a single dose of Exparel (a long-acting pain reliever) can provide pain relief for up to 72 hours after surgery, compared to a placebo. The study will be conducted in a prospective, randomized, double-blinded, placebo- controlled, and cross-over fashion.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
Media Library
- You are allergic to bupivacaine.I am unable to understand and give consent for medical procedures.I am not planning to join another clinical study while in this one.You cannot afford to pay for clinic visits or treatments.I have severe head or facial pain and have seen a specialist at the Stanford Pain & ENT clinic.I am younger than 18 or older than 80.
- Group 1: Exparel
- Group 2: Saline
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What are the odds of developing complications from Exparel (Bupivacaine Liposome)?
"While Phase 2 trials are not as well understood as Phase 3 trials, the available data suggests that Exparel (Bupivacaine Liposome) is safe."
Does Exparel (Bupivacaine Liposome) have a history of being effective?
"There are 124 different clinical trials currently underway to test Exparel (Bupivacaine Liposome), 20 of which are in Phase 3. Exparel (Bupivacaine Liposome) is being studied at 170 different research centres, with several located in Philadelphia, Pennsylvania."
Is this study seeking applicants who are under the age of 85?
"Eligible participants for this trial must be between 18-80 years old."
Are people being recruited for this experiment as of now?
"The clinical trial in question was last updated on October 24th, 2022, over half a year ago. Since then, it appears that the study has stopped looking for new patients to enroll. There are, however, 529 other trials that are still recruiting patients."
For what purpose is Exparel (Bupivacaine Liposome) most often employed?
"Exparel (Bupivacaine Liposome) provides an anesthetic solution for patients suffering from permphigus, acute nonspecific tenosynovitis, and general anesthesia."
How many individuals are currently testing this medication?
"This specific trial is no longer recruiting patients. The first posting was on December 1st, 2022 and the most recent update was on October 24th, 2022. However, there are still many other ongoing trials searching for participants that suffer from migraines (405) or are testing Exparel (Bupivacaine Liposome) (124)."
How can I sign-up to participate in this research project?
"This study is searching for 10 individuals who suffer from migraine and are between 18-80 years old. The most crucial qualifier for potential participants is that they must have Stanford Pain & ENT clinic visit related to craniofacial pain (migraine, cluster headache, trigeminal autonomic cephalgia, sphenopalatine ganglioneuraligia, paroxysmal hemicrania)."
Who else is applying?
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What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
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