Appendicitis Clinical Trials
Here are the 4 most popular medical studies for appendicitis
Anti-bacterial Agent
Antibiotic Irrigation for Appendicitis
This trial will compare two methods of preventing infection during surgery for appendicitis. One method uses a suction device without irrigation and the other uses a gentamicin/clindamycin solution.
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Appendicitis Clinical Trials With No Placebo
View 11 appendicitis medical studies that do not have a placebo group.
Sugammadex vs Neostigmine Reversal for Pediatric Appendectomy
This trial is testing two ways to reverse neuromuscular blockade. One group will get sugammadex and the other neostigmine/glycopyrrolate. The trial is notblinded, so the anesthesiologist will know which reversal method is being used.
Surgery
Appendectomy for Appendicitis
This trial is testing a new treatment for appendicitis that may be less invasive than surgery. Patients with appendicitis will be treated with antibiotics and, if they improve, will be discharged and monitored. If they do not improve, they will stay in the hospital for more treatment.
Frequently Asked Questions
Introduction to appendicitis
What are the top hospitals conducting appendicitis research?
When it comes to clinical trials focused on appendicitis, top hospitals across the United States are making significant strides in advancing our understanding and treatment of this common condition. In San Francisco, Zuckerberg San Francisco General Hospital is at the forefront with its active participation in one ongoing trial specifically dedicated to appendicitis. This hospital made history by recording their first ever appendicitis trial as recently as 2023.
Similarly, Jewish Hospital UL and University of Louisville Hospital, both located in Louisville, Kentucky, are actively engaged in a single appendicitis clinical trial each. These hospitals have also recorded their initial foray into appendicitis research very recently in 2023. The collaborative efforts of these institutions demonstrate a commitment to exploring innovative approaches for managing this condition.
In Winston-Salem, Wake Forest University Health Sciences is contributing valuable insights through its involvement in an active appendicitis trial. With their first recorded study occurring just last year (2023), they join the ranks of leading hospitals seeking breakthroughs for more effective management and treatment strategies.
Meanwhile, Johns Hopkins All Children's Hospital in Saint Petersburg stands out with two completed trials addressing appendicitis since embarking on their journey back in 2014. Their continued dedication to researching this condition showcases a long-standing commitment to improving outcomes for individuals affected by acute inflammation of the appendix.
These exemplary hospitals exemplify how medical professionals working hand-in-hand can drive progress forward even when faced with challenging conditions such as acute cases like an inflamed appendix; thereby ensuring that patients receive optimal care based on up-to-date knowledge and evidence-based practices
Which are the best cities for appendicitis clinical trials?
In terms of appendicitis clinical trials, certain cities stand out as leaders in research and development. Louisville, Kentucky takes the lead with 3 active trials focused on studying treatments like Under 65 complex appendicitis restricted duration and Restricted Duration of SOC Antibiotic Use. San Francisco, California closely follows with 2 ongoing studies exploring interventions such as Restricted Post-Operative Antibiotics Group and Restricted Duration of SOC Antibiotic Use. Miami, Florida also has 2 active trials investigating treatment options including Restricted Duration of SOC Antibiotic Use. Additional noteworthy locations include Hamilton, Ontario and Winston-Salem, North carolina with their respective contributions to the field. These cities offer individuals suffering from appendicitis access to cutting-edge clinical trials that pave the way for advancements in care and potential improvements in outcomes.
Which are the top treatments for appendicitis being explored in clinical trials?
Clinical trials are shedding light on new and innovative treatments for appendicitis. One promising option is sugammadex, currently being explored in an active trial. This novel treatment was first listed in 2023 and shows potential in addressing the challenges of this condition. Another avenue being investigated is the restricted duration of standard-of-care antibiotic use, which also has one active trial to its name since its listing in 2021. With ongoing research and development, these therapies offer hope for improved outcomes for patients suffering from appendicitis.
What are the most recent clinical trials for appendicitis?
Recent clinical trials have shed light on potential advancements in the management of appendicitis. One notable trial investigated the effectiveness of sugammadex, a medication used to reverse neuromuscular blockade, in treating appendicitis patients. Another study focused on the impact of restricted post-operative antibiotics on appendicitis outcomes. Additionally, low-dose group B1 and standard care with antibiotic instillation were evaluated as potential treatment options for this condition. Furthermore, rectus sheath block using 0.25% bupivacaine with 1:200 000 epinephrine was explored for its efficacy in managing appendicitis symptoms. These various trials offer hope for improved approaches to tackling this common surgical emergency.
What appendicitis clinical trials were recently completed?
A recent clinical trial investigating potential advancements in the treatment of appendicitis has been completed. In January 2019, Children's Mercy Hospital Kansas City successfully concluded a trial exploring the effectiveness of Sulfur hexafluoride lipid-type A microspheres. This study represents an important step forward in our understanding and management of appendicitis, offering hope for improved outcomes for patients affected by this condition.