Cluster Headache Clinical Trials
Here are the 0 most popular medical studies for cluster headache
CH Clinical Trials
View 6 CH medical studies.
Bupivacaine Liposome for Craniofacial Pain
“ I've had tn on the left side of my face for 8 years. It is now on my right side, too. I've tried various meds, nerve blocks, burning the nerve, etc. with little success.”
Vitamin D + Multivitamin for Cluster Headache
This trial is investigating whether high doses of Vitamin D3, plus a multivitamin, can help prevent cluster headaches. People in the US can participate by going to a participating lab for blood work (available in most of the US). The study includes a screening, a baseline period, and an experimental period where participants receive either high doses of Vitamin D3 or a placebo. There is also an open-label period where all participants receive the high doses of Vitamin D3. The primary outcome is the change in frequency of cluster headaches from the baseline to the experimental period.
Pain Biomarker Study for Pain
This trial investigates potential physical and molecular biomarkers for headaches, in order to improve our understanding of how these diseases work. Three different stimuli will be used - capsaicin, oxygen gas, and ice water - to see how they affect headache patients compared to controls.
Psilocybin for Cluster Headache
This trial is testing whether psilocybin, a compound found in some mushrooms, can help treat cluster headaches. People with cluster headaches will be given either a placebo or psilocybin in three sessions, separated by 5 days. They will keep a headache diary before, during, and after the sessions. After at least 6 months from the last session, they may be invited back for a second round of the trial.
Frequently Asked Questions
Introduction to cluster headache
What are the top hospitals conducting cluster headache research?
Cluster headaches, often described as the most excruciating type of headache one can experience, have prompted top hospitals across the United States to conduct clinical trials in search of effective treatments. In Chicago, the Diamond Headache Clinic leads the charge with three active cluster headache trials and six completed studies dedicated to this debilitating condition. This clinic has been at the forefront of cluster headache research since their first recorded trial back in 2002. Not far behind is Stanford University in California's prestigious Stanford town which currently hosts two ongoing cluster headache trials and boasts a total of two completed investigations since their pioneering study was documented in 2014.
Meanwhile, Michigan Headache and Neurological Institute located in Ann Arbor also stands out for its dedication to finding relief for those suffering from cluster headaches. With two active clinical trials underway and an additional three previous studies conducted since their inaugural investigation took place in 2014 they are slowly but surely progressing towards better understanding this challenging condition's underlying mechanisms.
The Ohio State University Wexner Medical Center situated within Columbus joins these efforts as well with its own pair of ongoing cluster headache trials and a significant achievement through completing two prior investigations commencing from 2014 onward; it serves as another beacon of hope for patients searching for solutions against these throbbing tormentors.
Lastly, The University of Texas Health Science Center at Houston rounds out our list by actively contributing through conducting two current cluster headache trials while adding four earlier ones under its belt dating back only five years ago up until recording them during initial analysis stages starting from 2016 onwards.
These esteemed institutions are committed not only to alleviating the agony experienced by those afflicted by cluster headaches but also advancing medical knowledge surrounding this perplexing disorder. By dedicating resources and expertise to clinical research, they offer renewed hope that breakthroughs may be on the horizon, bringing relief to millions worldwide who face daily battles against these relentless headaches
Which are the best cities for cluster headache clinical trials?
When it comes to cluster headache clinical trials, several cities demonstrate notable progress in research and treatment. Chicago, Illinois leads the way with 4 active trials focusing on various treatments such as Eptinezumab. Stanford, California is also making significant strides with 3 ongoing studies examining interventions like Exparel (Bupivacaine Liposome). Phoenix, Arizona and Lebanon, New Hampshire, California is also making significant strides with 3 ongoing studies examining interventions like Exparel (Bupivacaine Liposome). Phoenix, Arizona and Lebanon, New Hampshire share a similar dedication to advancement with 3 active trials each exploring potential breakthroughs for cluster headaches. Lastly, Houston, Texas joins the ranks of excellence by conducting 3 clinical trials investigating treatments like Eptinezumab along with Vitamin D supplementation and topical capsaicin application. These cities represent centers of innovation and hope for individuals suffering from cluster headaches seeking new therapeutic options through participation in clinical trials.
Which are the top treatments for cluster headache being explored in clinical trials?
Cluster headache treatment is an area of active exploration in clinical trials, with several promising options currently under investigation. Rimegepant, a recently listed drug in 2022, shows potential as a treatment for cluster headaches and has one ongoing trial dedicated to its evaluation. Similarly, Exparel (Bupivacaine Liposome), first listed in 2023, is being studied in one active trial for cluster headache patients. Eptinezumab and Vitamin D, Exparel (Bupivacaine Liposome), first listed in 2023, is being studied in one active trial for cluster headache patients. Eptinezumab and Vitamin D are also showing promise, with each having one active trial focused on their efficacy against cluster headaches. These treatments offer hope for those suffering from this debilitating condition and represent the cutting edge of research efforts in this field.
What are the most recent clinical trials for cluster headache?
Recent clinical trials have brought new hope for individuals suffering from cluster headaches, a debilitating condition. One such trial investigated the efficacy of Exparel (Bupivacaine Liposome), a promising treatment option in Phase 2. Additionally, Rimegepant demonstrated potential benefits in managing cluster headache symptoms during its Phase 2 trial. Furthermore, Vitamin D of Exparel (Bupivacaine Liposome), a promising treatment option in Phase 2. Additionally, Rimegepant demonstrated potential benefits in managing cluster headache symptoms during its Phase 2 trial. Furthermore, Vitamin D has shown promise as a therapeutic approach and is currently undergoing Phase 3 testing. Another candidate under evaluation is Eptinezumab, which completed its Phase 3 trial with encouraging results. Although still in an early stage of development (Phase 1), topical capsaicin also exhibited potential as a future treatment option for this excruciating disorder. These ongoing studies offer renewed optimism and progress towards alleviating the burden faced by those affected by cluster headaches.
What cluster headache clinical trials were recently completed?
In September 2021, H. Lundbeck A/S concluded an important clinical trial investigating the efficacy of Eptinezumab in managing cluster headaches. This study represents a significant milestone in the pursuit of improved treatments for this debilitating condition. The completion of this trial brings hope to individuals suffering from cluster headaches and highlights the commitment of researchers to finding innovative solutions for better management and relief.