Migraine Headache Clinical Trials
Here are the 0 most popular medical studies for migraine headache
Popular filter options for migraine headache trials
Migraine Clinical Trials
View 6 Migraine medical studies.
Behavioural Intervention
Osteopathic Manipulative Therapy (OMT) for Migraine
This study is evaluating whether Osteopathic Manipulative Therapy (OMT) can reduce migraine disability and severity scores when compared to standard of care including prophylactic pharmacological agents.
Corticosteroid
Dexamethasone +2 More for Migraine
The purpose of the study is assessment of the safety and efficacy of the De-Novo therapy in the treatment of craniofacial neuralgia and migraine headaches.This is an open-label study of simultaneous administration of combination of dexamethasone, lidocaine, and thiamine into the trigeminal nerve branches as well as greater and lesser occipital nerve bilaterally in one session. Patients who meet the exclusion and inclusion criteria are eligible for trial if they have experienced chronic migraine and craniofacial pain not responding to other prior therapies.
Phenothiazine Antipsychotic
Prochlorperazine for Migraine
Headache is a common presenting complaint to the emergency department accounting for 1-2% of patient visits. Of these headaches, approximately 90% are migraine, tension headache, or combined presentations. The most commonly used migraine therapy in the ED is intravenous prochlorperazine, but its administration requires close nursing observation, a bed, and the insertion of an intravenous catheter. Buccal prochlorperazine represents an alternative form of delivery that enables rapid achievement of therapeutic blood levels and may lead to symptom resolution. In a randomized, controlled, prospective study,the investigators plan to assess the efficacy of buccal versus intravenous prochlorperazine for the initial emergency department treatment of migraine headaches.
Behavioural Intervention
Mental Efficacy Workload Test (MEWT) +1 More for Migraine
Migraine headache occurs frequently in women more than men and is associated with symptoms not only of significant pain but also of symptoms typically including of photophobia, phonophobia, nausea and vomiting. Many migraine patients report difficulty in cognition from lack of concentration, difficulty in word finding or inability to remember. Many of these cognitive symptoms seem to be independent of the pain intensity and may occur completely separately from the headache pain but can be disabling. It is likely that the frequency and importance of cognitive symptoms associated with migraine are underreported. The Mental Efficacy Workload Test (MEWT) is a computerized battery that is designed to be an efficient and accurate measure of cognition during migraine headache. Treximet is a new migraine treatment recently FDA approved for the treatment for the relief of acute migraine that may be effective for the cognitive symptoms for migraine patients who have a history of cognitive dysfunction during a migraine headache. The primary efficacy parameter is to evaluate the effectiveness of treatment with Treximet versus placebo in patients with acute migraine headache measuring neuropsychological function using the MEWT during the migraine and comparing that score with a prior MEWT score when the patient had no migraine symptoms. A double blind, placebo-controlled, crossover study was chosen so that each patient may be her or his own control. It is the intent of this study to determine the type and intensity of cognitive dysfunction associated with migraine headache and to what extent that Treximet may relieve the cognitive dysfunction in a safe and effective manner.
MA Clinical Trials
View 6 MA medical studies.
Behavioural Intervention
Osteopathic Manipulative Therapy (OMT) for Migraine
This study is evaluating whether Osteopathic Manipulative Therapy (OMT) can reduce migraine disability and severity scores when compared to standard of care including prophylactic pharmacological agents.
Corticosteroid
Dexamethasone +2 More for Migraine
The purpose of the study is assessment of the safety and efficacy of the De-Novo therapy in the treatment of craniofacial neuralgia and migraine headaches.This is an open-label study of simultaneous administration of combination of dexamethasone, lidocaine, and thiamine into the trigeminal nerve branches as well as greater and lesser occipital nerve bilaterally in one session. Patients who meet the exclusion and inclusion criteria are eligible for trial if they have experienced chronic migraine and craniofacial pain not responding to other prior therapies.
Phenothiazine Antipsychotic
Prochlorperazine for Migraine
Headache is a common presenting complaint to the emergency department accounting for 1-2% of patient visits. Of these headaches, approximately 90% are migraine, tension headache, or combined presentations. The most commonly used migraine therapy in the ED is intravenous prochlorperazine, but its administration requires close nursing observation, a bed, and the insertion of an intravenous catheter. Buccal prochlorperazine represents an alternative form of delivery that enables rapid achievement of therapeutic blood levels and may lead to symptom resolution. In a randomized, controlled, prospective study,the investigators plan to assess the efficacy of buccal versus intravenous prochlorperazine for the initial emergency department treatment of migraine headaches.
Behavioural Intervention
Mental Efficacy Workload Test (MEWT) +1 More for Migraine
Migraine headache occurs frequently in women more than men and is associated with symptoms not only of significant pain but also of symptoms typically including of photophobia, phonophobia, nausea and vomiting. Many migraine patients report difficulty in cognition from lack of concentration, difficulty in word finding or inability to remember. Many of these cognitive symptoms seem to be independent of the pain intensity and may occur completely separately from the headache pain but can be disabling. It is likely that the frequency and importance of cognitive symptoms associated with migraine are underreported. The Mental Efficacy Workload Test (MEWT) is a computerized battery that is designed to be an efficient and accurate measure of cognition during migraine headache. Treximet is a new migraine treatment recently FDA approved for the treatment for the relief of acute migraine that may be effective for the cognitive symptoms for migraine patients who have a history of cognitive dysfunction during a migraine headache. The primary efficacy parameter is to evaluate the effectiveness of treatment with Treximet versus placebo in patients with acute migraine headache measuring neuropsychological function using the MEWT during the migraine and comparing that score with a prior MEWT score when the patient had no migraine symptoms. A double blind, placebo-controlled, crossover study was chosen so that each patient may be her or his own control. It is the intent of this study to determine the type and intensity of cognitive dysfunction associated with migraine headache and to what extent that Treximet may relieve the cognitive dysfunction in a safe and effective manner.
Frequently Asked Questions
Introduction to migraine headache
What are the top hospitals conducting migraine headache research?
While clinical trials for migraine headaches may be relatively limited, there are still hospitals working diligently to advance our understanding and treatment of this debilitating condition. In El Paso, the University Medical Center is leading the way with one active trial focused specifically on migraines. Despite having no previous trials recorded, their dedication to addressing this issue offers hope for those who suffer from chronic migraines in the region. Similarly, St. Luke's University Health Network in Bethlehem recognizes the pressing need for research and has initiated an active trial targeting migraine headaches as well. With zero past trials documented in their history, they strive to make a meaningful impact on the lives of individuals struggling with these excruciating headaches.
Moreover, VA Connecticut Healthcare System in West Haven is committed to providing comprehensive care not only to veterans but also actively engaging in a current clinical trial investigating migraines. While they have yet to conduct any previous studies related to this specific ailment, their involvement signifies recognition of its significance and prevalence among military personnel.
Additionally joining the effort is Corona Doctors Medical Clinics Inc located in Corona that has taken part in an ongoing clinical investigation specifically examining treatments for migraines; being new entrants within such domain hence no prior records relating directly towards cures of said affliction can presently been attributed besides these dedicated involvements. Lastly, Harbor-UCLA Medical Center located at Torrance holds similar ambitions by actively carrying out one innovative migraine headache clinical experiment aiming towards exploring possibilities while maintaining clean slate concerning past initiatives covering same concerns. Despite relatively low numbers of current or completed trials across these institutions so far ,each endeavor represents a step forward towards better understanding and management options for individuals suffering from debilitating migraine headaches that plague countless people worldwide
Which are the best cities for migraine headache clinical trials?
When it comes to migraine headache clinical trials, several cities have emerged as prominent centers for research. In Louisville, Kentucky, there are currently 2 active trials investigating treatments like Auricular Acupuncture. El Paso, Texas is also making strides with 1 ongoing trial focused on Dexamethasone and other interventions. Bethlehem, Pennsylvania follows suit with 1 active trial exploring the potential of Osteopathic Manipulative Therapy (OMT) among other approaches. Lastly, West Haven, Connecticut and Corona, California each contribute to the field with their own respective studies involving Psilocybin and a combination of Dexamethasone, Lidocaine,and Thiamine cohort. These cities offer individuals suffering from migraines access to cutting-edge clinical trials that may lead to improved management strategies and relief from this debilitating condition.
Which are the top treatments for migraine headache being explored in clinical trials?
The field of migraine headache treatment is rapidly advancing, with several innovative therapies being investigated in clinical trials. Leading the way is Eptinezumab, a promising drug currently being studied in four active clinical trials for migraine headaches. Another notable contender is Rimegepant, which has shown great potential and is undergoing evaluation in three ongoing trials. Additionally, Fremanezumab has emerged as a strong candidate and is currently involved in two clinical studies targeting migraine headaches. These cutting-edge treatments offer hope for individuals suffering from this debilitating condition, paving the way for improved quality of life and effective management strategies.
What are the most recent clinical trials for migraine headache?
Recent clinical trials have brought new hope for individuals suffering from migraines, with potential breakthroughs in treatment on the horizon. One of these trials explores the use of psilocybin, a psychedelic compound found in certain mushrooms, to alleviate migraine headaches. Early findings suggest promising results and pave the way for further research. Another trial investigates a combination therapy using dexamethasone, lidocaine, and thiamine as a potential solution for migraine relief. This multi-phase study aims to assess its effectiveness and safety profile. Additionally, researchers are examining the efficacy of buccal prochlorperazine in treating migraine headaches through a Phase 3 trial. These advancements offer optimism for improved management and quality of life for those affected by this debilitating condition.
What migraine headache clinical trials were recently completed?
Several recent clinical trials have investigated potential treatments for migraine headaches, bringing hope to those affected by this debilitating condition. One notable study focused on Ubrogepant, a medication under investigation as an acute treatment for migraines. Another trial examined the efficacy of Eptinezumab in preventing episodic and chronic migraines. Additionally, a trial exploring the use of Atogepant as a preventive therapy was also recently completed. These research endeavors demonstrate the ongoing efforts to develop new therapies that can provide relief and improve the quality of life for individuals suffering from migraine headaches.