Telephone-Based Support Programs for Epilepsy
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment BOOST, UPLIFT, Project UPLIFT, Using Practice and Learning to Increase Favorable Thoughts for epilepsy?
Research shows that telephone-based follow-up programs, like those used in cancer care and emergency medicine, can improve patient outcomes by providing education and addressing concerns. This suggests that similar telephone-based support programs for epilepsy could also be effective in improving patient care.12345
Is telephone-based support for epilepsy safe for humans?
How is the treatment BOOST, UPLIFT different from other treatments for epilepsy?
BOOST, UPLIFT is unique because it is a telephone-based program that combines cognitive-behavioral therapy and mindfulness to help manage depression in people with epilepsy. Unlike traditional treatments that may focus solely on medication, this program offers a non-drug approach to improve mental health and potentially reduce seizure activity by addressing depression.1112131415
What is the purpose of this trial?
This is a two-arm randomized controlled trial to compare telephone-based depression self-management (UPLIFT) to telephone-based support groups (BOOST). A sample of 120 English- and Spanish-speaking people with epilepsy (PWE) with elevated depressive symptoms will be enrolled. Both interventions are 8-week programs delivered in one-hour weekly sessions to groups of about 6 participants. Changes in depressive symptoms, quality of life and seizures will be assessed over 12 months. The trial will also examine mediators and moderators of treatment effects.
Research Team
Daniel Friedman, MD
Principal Investigator
NYU Langone Health
Tanya Spruill, PhD
Principal Investigator
NYU Langone Health
Eligibility Criteria
This trial is for adults over 18 with epilepsy diagnosed at least a year ago, who speak English or Spanish and are experiencing mild to moderate depression. They must be willing to have their group phone sessions recorded. People with severe depression, suicidal thoughts, significant cognitive issues, or active psychotic disorders cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either UPLIFT or BOOST intervention, which are telephone-based support programs for people with epilepsy, delivered in one-hour weekly sessions over 8 weeks
Follow-up
Participants are monitored for changes in depressive symptoms, quality of life, and seizures over 12 months
Treatment Details
Interventions
- BOOST
- UPLIFT
Find a Clinic Near You
Who Is Running the Clinical Trial?
NYU Langone Health
Lead Sponsor