Qudexy XR for Sick Headache
This study is evaluating whether a medication may help prevent migraines in children.
See full descriptionAbout the trial for Sick Headache
Treatment Groups
This trial involves 2 different treatments. Qudexy XR is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are in Phase 4 and have been shown to be safe and effective in humans.
Eligibility
This trial is for patients born any sex aged 18 and younger. There are 5 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether Qudexy XR will improve 1 primary outcome in patients with Sick Headache. Measurement will happen over the course of 16 Weeks.
Patient Q & A Section
Can sick headache be cured?
Although the effect of treatment in this study did not correspond directly to the subjective improvement, the study results support the possibility of a successful treatment of sick headache. Further, the study findings can be used as a basis for considering more individual therapy options.
What is sick headache?
Although sick headache can present with a wide range of symptoms, the most common presenting complaint is headache. Atypical headache characteristics such as nausea/vomiting, dysphagia, dysarthria, dysphasia and syncope have predictive value for cerebral and/or intracranial lesions in head CT. Clinicians can use this information to accurately and quickly rule out intracranial pathology that may be responsible for such symptoms.
What are the signs of sick headache?
Sick headache is a common phenomenon in primary care and it is common to seek medical advice only when it is severe or lasts longer than three days. Primary care should be familiar with the symptoms and signs of sick headache as they will help them to formulate a differential diagnosis.
How many people get sick headache a year in the United States?
About 7.6 million, or 27%, of the American population has at least one reported case of sickness headache in a given year. More than 1.7 million adults (10%) are affected by sickness headache at least a few times every year. About 75,000-110,000 persons seek medical care for sickness headache each year. As a group, adults without health insurance are more likely to suffer from sickness headache, but a large part of the variation in prevalence is attributable to differences in age, sex and race/ethnicity. A history of a head trauma was associated with an increased risk in only 2 of 6 subgroups.
What causes sick headache?
Sick headache is frequently associated with other medical or psychiatric problems. Patients should be approached for these potential interactions to formulate a diagnosis and management plan. The diagnosis of sick headache is difficult for two reasons. First, typical manifestations of sick headache are often overshadowed by the myriad of psychiatric and neurologic problems present in a substantial number of patients. Furthermore, an acute headache with focal deficit may also signify different, and potentially life-threatening, pathologies such as brain stem compression, a cerebral hemorrhage, or intracranial mass. More study is needed to better quantify the prevalence, etiology, and effects of sick headaches in the general population.
What is qudexy xr?
Qudexy/Xr/Xs has not been used for headache, dizziness, or vision problems before. The FDA said the drug could cause serious heart and lung problems and should be used carefully. The label warns that it can cause dizziness, confusion, and ataxia, as well as heart palpitations, chest pains, shortness of breath, and swelling of the hands and feet. In addition, the label also warns that patients who already have heart problems may suffer further impairment and that women who are pregnant should not take the drug because of its potential for harm to their children.
What is the primary cause of sick headache?
In most patients with sick headaches, there seems to be a single primary headache disorder. We suggest that the most prevalent primary headache disorder is episodic tension-type headache. Once a diagnosis of primary headaches becomes known, physicians need to be aware of [sickle cell disease, vasculitis, sarcoidosis, fibromyalgia, and rheumatoid arthritis or spondyloarthritis] as possible secondary causes of sick headache.
Is qudexy xr typically used in combination with any other treatments?
Results from a recent clinical trial, qudexy XR was typically used in combination with aspirin which is frequently used for the prophylaxis of secondary headache. Results from a recent clinical trial has only a small sample size and the results need to be verified in additional patient numbers.
What is the average age someone gets sick headache?
The average age of sih headache is 20 years. Older patients are reported to be more likely to present headache than younger patients. There is a wide demographic variability in the prevalence of sih headache according to age class and sex. There is no significant difference of sih headache on the basis of ethnicity. Age is the most important factor affecting the condition.
Is qudexy xr safe for people?
In the absence of compelling indications, qudexy xr is not recommended for the routine use in people, because most adults who receive qudexy xr develop clinically significant symptoms, usually within the first twelve weeks.