LED Therapy for Traumatic Brain Injury
(LED-TBI Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests if special lights can help people with brain injuries by making their brain cells work better. It aims to improve memory, sleep, and overall quality of life. Previous research has shown that using these lights after a brain injury can protect brain cells.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
Is LED therapy safe for humans?
LED therapy, including red and near-infrared light, is generally considered safe for humans. Studies have shown that it is noninvasive, painless, and does not cause serious side effects. Some mild skin reactions like temporary redness or darkening may occur, but no serious adverse events have been reported.12345
How does LED therapy differ from other treatments for traumatic brain injury?
LED therapy for traumatic brain injury is unique because it uses red and near-infrared light to improve brain function by enhancing blood flow and cellular energy without being invasive or causing pain. This treatment is non-thermal and can be administered at home, making it different from other more invasive or drug-based therapies.23567
What data supports the effectiveness of LED therapy for traumatic brain injury?
Who Is on the Research Team?
Yelena Bogdanova, PhD PhD
Principal Investigator
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
Are You a Good Fit for This Trial?
This trial is for English-speaking adults aged 21-55 who have experienced a mild traumatic brain injury (TBI) with loss of consciousness for no more than 30 minutes. It's specifically aimed at active-duty personnel or veterans exposed to blasts. People with penetrating head injuries, previous neurological or psychotic disorders, or significant hearing or vision impairments cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either active LED treatment or sham LED treatment to improve cognition and neuropsychiatric status
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- LED
- sham LED
Find a Clinic Near You
Who Is Running the Clinical Trial?
VA Office of Research and Development
Lead Sponsor