Ethanol + Cannabinoid Effects on DUI
(THC-ETOH Trial)
Trial Summary
Do I need to stop taking my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the drug combination of Active delta-9-THC and Active Ethanol on driving under the influence (DUI)?
Is it safe to combine ethanol and cannabinoids?
How does the drug combination of ethanol and delta-9-THC affect driving impairment compared to other treatments?
The combination of ethanol and delta-9-THC is unique because it can significantly enhance driving impairment in an additive or even synergistic manner, compared to when each is used alone. This combination affects perceptual, cognitive, and motor functions more than either substance individually, making it particularly important to study in the context of driving under the influence.69101112
What is the purpose of this trial?
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
Eligibility Criteria
This trial is for men and women aged 21 to 55 who have used cannabis and alcohol at least once. They must be able to understand and agree to the study's terms. Pregnant individuals, those who've never consumed alcohol or cannabis, or people with hearing problems cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive ethanol and/or THC to study their effects on simulated driving and cognition
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Active delta-9-THC
- Active Ethanol
Find a Clinic Near You
Who Is Running the Clinical Trial?
Yale University
Lead Sponsor