This trial is a multicenter, placebo-controlled, parallel group randomized trial with blinding of participants and observers with the goal of comprehensively assessing the effect of high-dose IV ketamine infusion (1 mg.kg-1.h-1 for six hours) on the frequency and intensity of headaches, mood, activity, sleep, quality of life and safety of ketamine for three months after the interventions.
1 Primary · 14 Secondary · Reporting Duration: At 1 month, 2 months and 3 months
56 Total Participants · 2 Treatment Groups
Primary Treatment: Ketamine infusion · Has Placebo Group · Phase 3
Age 18+ · All Participants · 3 Total Inclusion CriteriaMark “Yes” if the following statements are true for you: