Exercise for Mild Cognitive Impairment

Sunnybrook Health Sciences Centre, Toronto, Canada
Mild Cognitive Impairment+1 More ConditionsExercise - Other
All Sexes

Study Summary

This trial looks at whether combining exercise with transcranial direct current stimulation, a type of brain stimulation, can help improve memory in people with mild cognitive impairment or Alzheimer's disease.

Eligible Conditions
  • Mild Cognitive Impairment
  • Alzheimer's Disease

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3

Study Objectives

1 Primary · 4 Secondary · Reporting Duration: Change over 2 weeks Baseline to Endpoint

Week 2
Change in cognition: The Word Recall Task from the Alzheimer's Disease Assessment Scale-Cog (ADAS-Cog)
Change in cognition: The Word Recognition Task from the Alzheimer's Disease Assessment Scale Cog (ADAS-Cog)
Change in cognition: n-back reaction time
Change in neuropsychiatric symptoms: The Neuropsychiatric Inventory (NPI)
Changes in concentration of blood biomarkers of brain plasticity
Week 2
Change in cognition: n-back accuracy
Week 2
Change in global cognitive function: The Montreal Cognitive Assessment (MoCA) Total Scores

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

1 Treatment Group

Exercise and tDCS
1 of 1

Experimental Treatment

60 Total Participants · 1 Treatment Group

Primary Treatment: Exercise · No Placebo Group · N/A

Exercise and tDCSExperimental Group · 2 Interventions: Exercise, tDCS · Intervention Types: Other, Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: change over 2 weeks baseline to endpoint

Who is running the clinical trial?

Sunnybrook Health Sciences CentreLead Sponsor
615 Previous Clinical Trials
1,470,506 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 1 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have been diagnosed with Alzheimer's disease or a combination of Alzheimer's disease and vascular disease that affects your thinking and memory capabilities.

Frequently Asked Questions

Are there any remaining openings for participants in this research?

"Clinicaltrials.gov indicates that this trial, first posted on November 28th 2018 and recently updated February 25th 2022, is actively enrolling participants." - Anonymous Online Contributor

Unverified Answer

How many participants are accepted into this research project?

"Affirmative. The clinicaltrials.gov platform reveals that this research is currently accepting participants, which originated on November 28th 2018 and was last modified on February 25th 2022. 60 people need to be recruited from one medical site." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.