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Behavioural Intervention

Personalized tDCS for Motivation

N/A
Waitlist Available
Led By Sumientra M Rampersad, PhD
Research Sponsored by Northeastern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 week
Awards & highlights

Study Summary

This trial will use electric brain stimulation to improve memory in elderly people by modulating a key brain region associated with motivation.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 week
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 week for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in "Estimates of effort" from baseline
Change in "Feeling of difficulty" from baseline
Change in "NASA Task Load Index" from baseline
+1 more
Secondary outcome measures
Change in "California Verbal Learning Test" score from baseline
Change in "Intrinsic functional connectivity strength" from baseline
Change in "Memory recognition discriminability (d')" from baseline

Trial Design

4Treatment groups
Experimental Treatment
Placebo Group
Group I: Personalized tDCSExperimental Treatment1 Intervention
Transcranial direct current stimulation (tDCS) will be individually optimized to simultaneously stimulate key nodes connected to mid-cingulate cortex, including anterior insula, MFG and supramarginal gyrus.
Group II: Indirect tDCSExperimental Treatment1 Intervention
Transcranial direct current stimulation (tDCS) was computationally optimized to target the middle frontal gyrus, a brain area connected to mid-cingulate cortex.
Group III: Direct tDCSExperimental Treatment1 Intervention
Transcranial direct current stimulation (tDCS) was computationally optimized to target mid-cingulate cortex directly.
Group IV: Sham tDCSPlacebo Group1 Intervention
Placebo transcranial direct current stimulation (tDCS) will be applied.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Personalized tDCS
2020
N/A
~40

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalOTHER
2,933 Previous Clinical Trials
13,198,429 Total Patients Enrolled
Northeastern UniversityLead Sponsor
88 Previous Clinical Trials
61,238 Total Patients Enrolled
National Institute on Aging (NIA)NIH
1,672 Previous Clinical Trials
28,018,591 Total Patients Enrolled
1 Trials studying Motivation
422 Patients Enrolled for Motivation

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
TDCS to Improve Motivation and Memory in Elderly (TIME)
Sumientra Rampersad 2020. "TDCS to Improve Motivation and Memory in Elderly (TIME)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04268186.
All > Memory
~14 spots leftby Apr 2025
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