Pain Management Clinical Trials
Here are the 6 most popular medical studies for pain management
Biological
Placental Tissue Extract Injection for Degenerative Disc Disease
This trial will test a new potential treatment for degenerative disc disease, by injecting a product derived from human tissue into the affected disc. The goal is to find a safe and effective way to treat the condition.
Procedure
Sociocultural Influences on Pain Assessment
This trial is exploring if social and cultural factors play a role in how people experience pain and how others interpret it. Eligible participants will be asked to complete a series of tests that may include electric shock, thermal stimulation, and viewing images of others in pain.
Popular filter options for pain management trials
Anxiety Clinical Trials
View 8 Anxiety medical studies.
Behavioral Intervention
Acceptance and Commitment Therapy for Postoperative Pain After Knee Replacement
This trial is testing whether Acceptance and Commitment Therapy (ACT) is more effective than Attention Control (AC) in reducing postoperative pain and improving functioning in at-risk Veterans undergoing total knee arthroplasty (TKA).
Behavioral Intervention
Sudarshan Kriya Yoga for PTSD
This trial will study the effects of a virtually-delivered Sudarshan Kriya Yoga intervention on symptoms of PTSD, depression, pain, anxiety, and quality of life in Canadian military and RCMP veterans, compared to a waitlist control.
Phase 3 Chronic Pain Clinical Trials
View 91 phase 3 chronic pain medical studies.
Behavioral Intervention
Acceptance and Commitment Therapy for Postoperative Pain After Knee Replacement
This trial is testing whether Acceptance and Commitment Therapy (ACT) is more effective than Attention Control (AC) in reducing postoperative pain and improving functioning in at-risk Veterans undergoing total knee arthroplasty (TKA).
Corticosteroid
PRP vs Corticosteroid Injections for Shoulder Osteoarthritis
This trial is testing whether a new treatment, platelet-rich plasma (PRP) derived from autologous blood, is effective in treating shoulder OA in young active duty and civilian populations.
Chronic Pain Clinical Trials With No Placebo
View 91 chronic pain medical studies that do not have a placebo group.
Analgesic
IV vs Oral Acetaminophen for Surgical Pain
This trial investigates if there is a difference in pain relief between intravenous and oral acetaminophen given before surgery. The hypothesis is that the intravenous form does not provide better pain relief or decrease opioid use compared to the oral form.
Paid Chronic Pain Clinical Trials
View 91 chronic pain medical studies that offer remuneration.
General Anesthetic
Anesthetics for Pain Management During Surgery
This trial will test how pain affects long-term memory and the body's conditioned responses, using MRI to track the brain's reaction. The study will take place over 5 visits, with no long-term follow up required.
Anti-Inflammatory Drug + Pain Challenge for Pain
This trial will study whether a new bio-signature (a range of pro- and anti-nociceptive IL-1 family cytokine activity) can predict pain and release of endogenous opioids in healthy subjects. Another objective is to see if an anti-inflammatory drug (minocycline) will reduce pain during the experimental, nociceptive pain challenge.
View More Pain Management Trials
See another 59 medical studies focused on pain management.
Frequently Asked Questions
Introduction to pain management
What are the top hospitals conducting pain management research?
When it comes to advancing pain management techniques, several top hospitals across the United States are leading the way. In Brooklyn, Maimonides Medical Center has emerged as a pioneer in this field with three active pain management trials and a total of 18 completed studies. The hospital first delved into pain management research in 2013, aiming to provide innovative solutions for those suffering from chronic or acute discomfort. Meanwhile, the prestigious Mayo Clinic in Rochester is also making significant strides with its three ongoing trials and an impressive history of 19 past investigations conducted since their inaugural pain management trial in 2005.
Heading down south to Nashville, Vanderbilt University Medical Center demonstrates its commitment to improving pain management practices through two currently active clinical trials and seven previously conducted studies dating back to their initial exploration of this field in 2003. Boston's Brigham and Women's Hospital joins this cohort of esteemed institutions by offering two ongoing pain management trials alongside a noteworthy record of 16 prior investigations since initiating their pioneering trial back in 2001.
Lastly but not least, located at the heart of Gainesville lies the University of Florida - renowned for its contributions toward innovative approaches to managing various kinds of physical distress. Their dedication shines through with two current pain management trials complemented by twelve accomplished ones stretching all the way back from when they initiated their first-ever study on managing painful conditions sixteen years ago during2021
These leading hospitals' efforts demonstrate that there is hope for individuals living with both short-term and long-term debilitating discomforts like never before. By pushing boundaries through rigorous scientific investigation and collaborative patient care, these institutions bring us closer than ever towards finding effective strategies that can alleviate suffering while enhancing overall quality-of-life standards.
Which are the best cities for pain management clinical trials?
When it comes to pain management clinical trials, several cities have emerged as key hubs for innovative research. New york, New York leads the pack with 9 active trials exploring treatments like Pain Evaluation and BPISF, Non-stiff Intravenous Hydrocortisone, and Sana Pain Reliever. Indianapolis, Indiana closely follows with 8 ongoing studies focused on various treatment approaches. Toronto, Ontario also demonstrates its commitment to advancing pain management with 7 active trials investigating treatments including Group 3 and Cryoneurolysis Group. These cities represent important centers for cutting-edge research in the field of pain management clinical trials.
Which are the top treatments for pain management being explored in clinical trials?
[Pain management](https://www.withpower.com/clinical-trials/pain-management) research is at the forefront of medical exploration, with several promising treatments currently being investigated in clinical trials. Leading the pack is the acetaminophen/naproxen sodium fixed combination, undergoing two active trials since its initial listing in 2023. Following closely behind is intranasal fentanyl (2 mcg/kg), which has shown great potential with one ongoing trial and debuted in 2022. Also making waves is a simple yet effective solution: 10 mL 2% lidocaine, garnering attention with one active trial and first listed in 2021. With each study conducted, we move closer to breakthroughs that could transform pain management for patients worldwide.
What are the most recent clinical trials for pain management?
Exciting advancements are underway in the realm of pain management, as recent clinical trials offer new possibilities for relief. One such trial focuses on the effectiveness of EMLA cream, which has entered Phase 4 and aims to alleviate pain effectively. Additionally, a study specifically targets the population experiencing chronic pain to evaluate alternative management strategies. Another notable trial investigates the potential benefits of an acetaminophen/naproxen sodium fixed combination in mitigating discomfort. Furthermore, researchers explore oral immediate-release oxycodone 10mg as a viable option for managing pain symptoms. Additionally, there is ongoing research into ABC block with bupivacaine and liposomal bupivacaine to enhance current methods of pain management. These recent clinical trials hold promise for improved care and enhanced well-being among individuals suffering from various types of acute or chronic pain conditions.
What pain management clinical trials were recently completed?
Recent clinical trials have made significant strides in the field of pain management, offering hope for improved treatments. In October 2021, the University of Wisconsin, Madison completed a trial investigating Liposomal bupivacaine's potential to alleviate pain. Meanwhile, in September 2021, NorthShore University HealthSystem concluded their study on low-dose naltrexone as a means of managing pain. Additionally, January 2021 saw the completion of a mindfulness trial conducted by the University of California, San Diego. These advancements represent diligent efforts by researchers to address and alleviate chronic pain conditions using innovative approaches.