Reviewed by Michael Gill, B. Sc.
25 Lower Back Pain Clinical Trials Near Me
Top Hospitals for Lower Back Pain Clinical Trials
Image of The University of Utah Healthcare System in Utah.
The University of Utah Healthcare System
Salt Lake City
2Active Trials
5All Time Trials for Lower Back Pain
2011First Lower Back Pain Trial
Image of Johns Hopkins University in Maryland.
Johns Hopkins University
Baltimore
2Active Trials
4All Time Trials for Lower Back Pain
2016First Lower Back Pain Trial
Top Cities for Lower Back Pain Clinical Trials
Image of San Diego in California.
San Diego
4Active Trials
SpineZoneTop Active Site
Top Treatments for Lower Back Pain Clinical Trials
Treatment Name
Active Lower Back Pain Clinical Trials
All Time Trials for Lower Back Pain
First Recorded Lower Back Pain Trial
Physical Therapy
2
12
2011
ED Physical Therapy
2
2
2021
ABCp
1
1
2021
self-administered acupressure
1
1
2022
Group-supervised physiotherapy training programs
1
1
2022
Recently Completed Studies with FDA Approved Treatments for Lower Back Pain
Treatment
Year
Sponsor
LY3526318
2021
Eli Lilly and Company
LY3556050
2021
Eli Lilly and Company
LY3016859
2020
Eli Lilly and Company

What Are Low Back Pain Clinical Trials?

Low back pain (LBP) is a musculoskeletal condition that affects 65-85% of the population and is common in adults between the ages of 30 and 50. It is one of the leading disabling conditions among individuals aged 60 years or older. While there are several treatment options for LBP, many of them result in poor outcomes. Research also claims that less than 50%of physicians are confident in their diagnosis of LBP in the elderly.

The lack of understanding of the causes and treatment of LBP has made it the subject of numerous clinical trials.

Why Is Low Back Pain Being Studied Through Clinical Trials?

The discomfort caused by low back pain can be acute or chronic. Even when the elderly undergo treatment, the pain is minimized only temporarily. As a result, the patients suffer from restless sleep and poor lifestyle.

According to a study conducted by the Department of Rehabilitation Medicine, University of Washington Medical Center, LBP causes “sleep disturbances, psychological distress, withdrawal from social and recreational activities, impeded cognition, rapid deterioration of functional ability, malnutrition, and falls.”

To help LBP patients improve their quality of life and eradicate discomfort, numerous clinical trials are taking place to find the best methods of diagnosis and treatment.

What Are The Types of Treatments Available For Low Back Pain Problems?

A wide range of treatment options is applied for low back pain. Physicians adjust and combine several treatments based on age, cause, and type of low back pain. These treatments include:

  • Physical therapy
  • Alternative treatments
  • OTC pain relievers
  • Prescription medications
  • Injection-based procedures
  • Exercise
  • Diet
  • Lifestyle modification
  • surgery

What Are Some Recent Breakthrough Clinical Trials For Low Back Pain Issues?

2020 – Published by Wolters Kluwer Health, Inc. on behalf of the International Association for the Study of Pain, this was the first study that found an effective long-term solution for low back pain with a 10 mg dose of tanezumab. The drug provided pain relief and functional improvement in patients with difficult-to-treat, chronic low back pain.

2018 – A randomized clinical trial discovered that a low-dose Amitriptyline might be an effective treatment for chronic low back pain and a better alternative to opioids. The study found the dose to be effective in the reduction of disability at 3 months of usage.

Who Are Some Of The Key Opinion Leaders / Researchers / Institutions Conducting Low Back Pain Clinical Trial Research?

Jeannie Bailey – An assistant professor at Orthopaedic Surgery School of Medicine, Bailey has received numerous accolades for her contribution to numerous studies involving lumbar spinal conditions and low back pain. Her research explores new techniques for identifying clinical-relevant biomechanical phenotypes and exploring potential interactive mechanisms between separate musculoskeletal pain phenotypes. She is currently active in multiple ongoing clinical trials involving chronic low back pain.

SBPR – The Society for Back Pain Research has promoted clinical and scientific studies involving back pain since 1971. The organization focuses on researching causes, treatment, and prevention methods for back pain.

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 16th, 2021

Last Reviewed: November 29th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

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