← Back to Search

Behavioural Intervention

Yoga-Based Stretching for Inflammation

N/A
Waitlist Available
Led By Peter M Wayne, PhD
Research Sponsored by Harvard University Faculty of Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age between 40 - 60 years old
Healthy adults
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 0-, 30-, 60-, 120-, 180-minutes and 24 hours post intervention.
Awards & highlights

Study Summary

This trial will test how two types of yoga-based stretching affects levels of inflammation in people who have never done yoga before.

Who is the study for?
This trial is for healthy, non-smoking adults aged 40-60 with a BMI of 19-29. It's not suitable for those with fractures in the last 3 years, pregnant individuals, regular intense exercisers, those with significant soft tissue injuries or metal implants in areas to be stretched, substance abusers, anyone with chronic inflammation or recent acute illness, recent vaccinations, medication use within a week prior to the study start date, endocrine disorders like diabetes or conditions causing joint hypermobility.Check my eligibility
What is being tested?
The study examines how two types of yoga-based stretching (mild and intense) affect inflammatory markers and healing molecules in people who haven't done much yoga before. Researchers will measure changes in Systemic Inflammatory Cytokines and Specialized Pro-resolving Mediators after these stretching sessions.See study design
What are the potential side effects?
Yoga-based stretching is generally safe but may include mild discomfort or muscle soreness especially if participants are new to yoga. Intense stretches might lead to more pronounced muscle soreness or strain.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 40 and 60 years old.
Select...
I am a healthy adult.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 0-, 30-, 60-, 120-, 180-minutes and 24 hours post intervention.
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 0-, 30-, 60-, 120-, 180-minutes and 24 hours post intervention. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Feasibility of a pilot study including one session of acute stretching and serial blood samples over a period of 24 hours.
Secondary outcome measures
Specialized pro-resolving mediators (SPMs)
Systemic inflammatory cytokines

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Stretching protocol 2, Intense Stretching Group (ISG):Experimental Treatment1 Intervention
The protocol starts with 5 minutes of instruction about finding a range of stretching representing approximately 100% of the range of motion and pain-free. The instructor will also wear wrist and ankle reflective bands as body-marks to show a posture with 100% stretch. Once the participant grasps the concept the routine will begin with 5 minutes of warm-up, followed by stretching exercises targeting 10 anatomical groups. Each posture will last 1 minute divided in 30 seconds of settling into each posture and 30 seconds of holding. Each session will be video recorded to analyze the stretching range, only if the participant agrees at the informed consent visit. Participants will be encouraged to find their own 100% with some feedback from the instructor.
Group II: Stretching protocol 1, Mild Stretching Group (MSG)Experimental Treatment1 Intervention
The protocol starts with 5 minutes of instruction about finding a range of stretching representing approximately 50% of the range of motion and pain-free. The instructor will also wear wrist and ankle reflective bands as body-marks to show a posture with 100% stretch and then corrected to 50%. Once the participant grasps the concept the routine will begin with 5 minutes of warm-up, followed by stretching exercises targeting 10 anatomical groups. Each posture will last 1 minute divided in 30 seconds of settling into each posture and 30 seconds of holding. Each session will be video recorded to analyze the stretching range, only if the participant agrees at the informed consent visit. Participants will be encouraged to find their own 50% with some feedback from the instructor.
Group III: Control group (CG)Active Control1 Intervention
Those subjects randomized to the CG will be offered reading options that do not evoke high emotional distress. They will spend an hour reading.

Find a Location

Who is running the clinical trial?

Harvard University Faculty of MedicineLead Sponsor
14 Previous Clinical Trials
23,514 Total Patients Enrolled
Peter M Wayne, PhDPrincipal InvestigatorBrigham and Women's Hospital and Harvard University
2 Previous Clinical Trials
92 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~1 spots leftby May 2024