Popular Trials
Biological
Placental Tissue Extract Injection for Degenerative Disc Disease
This trial will test a new potential treatment for degenerative disc disease, by injecting a product derived from human tissue into the affected disc. The goal is to find a safe and effective way to treat the condition.
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Trials for Opioid Use Disorder Patients
Positive Airway Pressure Device
CPAP for Sleep Apnea in Opioid Users
This trial will study whether people with chronic pain who use opioids and have sleep disordered breathing might benefit from using a device that provides continuous positive airway pressure during sleep.
Phase 3 Trials
Behavioral Intervention
Acceptance and Commitment Therapy for Postoperative Pain After Knee Replacement
This trial is testing whether Acceptance and Commitment Therapy (ACT) is more effective than Attention Control (AC) in reducing postoperative pain and improving functioning in at-risk Veterans undergoing total knee arthroplasty (TKA).
Corticosteroid
PRP vs Corticosteroid Injections for Shoulder Osteoarthritis
This trial is testing whether a new treatment, platelet-rich plasma (PRP) derived from autologous blood, is effective in treating shoulder OA in young active duty and civilian populations.
Trials With No Placebo
Analgesic
IV vs Oral Acetaminophen for Surgical Pain
This trial investigates if there is a difference in pain relief between intravenous and oral acetaminophen given before surgery. The hypothesis is that the intravenous form does not provide better pain relief or decrease opioid use compared to the oral form.
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Frequently Asked Questions
Introduction to pain
What are the top hospitals conducting pain research?
When it comes to advancing our understanding and treatment of pain, several top hospitals are leading the charge. In Brooklyn, Maimonides Medical Center has made significant strides with three ongoing pain trials and a total of 18 completed studies in this field. Their first recorded pain trial took place in 2013, showcasing their commitment to staying at the forefront of pain research. The renowned Mayo Clinic in Rochester is also making impressive contributions with three active pain trials and a track record of 19 past studies since initiating their first trial in 2005.
Meanwhile, Vanderbilt University Medical Center in Nashville focuses on addressing pain through two ongoing clinical trials and seven previously conducted ones since embarking on their inaugural study back in 2003. Brigham and Women's Hospital, located in Boston, shares a similar dedication by currently conducting two active pain trials while having an accomplished history of 16 previous investigations dating back to their first recorded trial in 2001.
Lastly, the University of Florida based in Gainesville plays a crucial role as well with its involvement in two current pain trials and twelve prior studies that began with their inaugural investigation taking place alongside Mayo Clinic’s initial effort both during the year -2005.
These esteemed institutions highlight not only the importance but also the complexity surrounding chronic pain management. Through collaborative efforts like these clinical trials across various locations nationwide we can move closer towards finding better solutions for those suffering from chronic or acute forms of this condition; ensuring improved quality of life for patients everywhere
Which are the best cities for pain clinical trials?
When it comes to pain clinical trials, several cities emerge as top destinations for cutting-edge research. New york, New York leads the way with 9 active trials focusing on various treatments like Pain Evaluation and BPISF, Non-stiff Intravenous Hydrocortisone, and Sana Pain Reliever. Indianapolis, Indiana follows closely behind with 8 ongoing studies exploring different treatment approaches. Toronto, Ontario also ranks high in the list with 7 active trials investigating potential treatments like Group 3 and Cryoneurolysis Group. These cities offer individuals suffering from chronic pain access to innovative clinical trials that may lead to improved management and relief.
Which are the top treatments for pain being explored in clinical trials?
In the realm of pain management, clinical trials are exploring a range of treatments to alleviate discomfort. Topping the list is the promising Acetaminophen/Naproxen Sodium Fixed Combination, currently being tested in two active trials dedicated to pain relief. A newcomer on the scene, Intranasal Fentanyl (2 mcg/kg), shows promise in its first listed trial for providing effective pain control. Another contender making waves is 10 mL 2% lidocaine, with one ongoing trial showcasing its potential as a treatment option. As researchers delve deeper into these innovative approaches, they bring us closer to finding improved solutions for managing and reducing pain effectively.
What are the most recent clinical trials for pain?
Recent clinical trials have brought new possibilities in the realm of pain management. One notable study examined the efficacy of EMLA Cream, which has shown promising results in alleviating pain. Additionally, a phase 4 trial explored the use of ABC block with bupivacaine and liposomal bupivacaine as a potential solution for pain relief. Another trial focused on the benefits of acetaminophen/naproxen sodium fixed combination in managing pain. Lastly, an investigation into oral immediate-release oxycodone 10mg offers insights into its effectiveness as a treatment option for pain management. These ongoing studies offer hope and advancements to address various types and causes of physical discomfort effectively.
What pain clinical trials were recently completed?
Recent advancements in pain management research have yielded valuable insights through the completion of various clinical trials. Notably, a study sponsored by the University of Wisconsin, Madison concluded in October 2021, examining the efficacy of Liposomal bupivacaine. In September 2021, NorthShore University HealthSystem successfully completed a trial investigating low-dose naltrexone. Additionally, an investigation into Mindfulness conducted by the University of California, San Diego came to fruition in January 2021. These studies contribute to our understanding of pain treatment and pave the way for potential breakthroughs that could enhance patients' quality of life.