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Strength vs Power Training for Patellofemoral Pain (STRIPE Trial)
N/A
Recruiting
Led By Neal Glaviano, PhD
Research Sponsored by University of Connecticut
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Participants to be between the ages of 18-40 years old.
Insidious onset of symptoms greater than 3 months.
Must not have
History of patella subluxation, meniscal injury or ligamentous instability.
History of lower extremity surgery.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up immediately after the intervention and then 6, 12, 18, and 24 months post-intervention.
Awards & highlights
Summary
This trial tests a new exercise program called STRIPE for people with persistent knee pain. The program aims to build muscle strength and power to reduce pain and prevent it from coming back.
Who is the study for?
This trial is for people aged 18-40 with patellofemoral pain that started on its own over 3 months ago and hurts at least a bit during activities like sitting long, jumping, or climbing stairs. It's not for those with other knee issues, history of knee cap dislocation, meniscus or ligament injuries, leg surgery, or pain from the lower back.
What is being tested?
The study compares two 6-week rehab programs for knee pain: Standard of Care (SOC) vs. Strength Training with Power Exercises (STRIPE). It will check which program better reduces pain and prevents it from coming back while improving leg strength and squatting form.
What are the potential side effects?
While specific side effects aren't listed here, exercise-based rehab can sometimes lead to muscle soreness, joint discomfort or exacerbation of existing symptoms if not done correctly.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am between 18 and 40 years old.
Select...
My symptoms started slowly over more than 3 months ago.
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I have had issues with my kneecap, meniscus, or ligaments.
Select...
I have had surgery on my leg or foot.
Select...
I have experienced pain that spreads from my lower back.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ immediately after the intervention and then 6, 12, 18, and 24 months post-intervention.
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~immediately after the intervention and then 6, 12, 18, and 24 months post-intervention.
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Change in hip adduction during a single leg squat
Change in hip rate of torque development
Change in knee pain.
+3 moreSecondary study objectives
Change in cognitive factors
Change in coping strategy
Change in physical activity
+2 moreTrial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Strength Training Rehabilitation Incorporating Power Exercises (STRIPE)Experimental Treatment1 Intervention
Those in the STRIPE group will complete two power and one strength training sessions a week. All participants will be provided an educational pamphlet and exercises will be divided into four components - hip abductors, hip extensors, core, and quadriceps muscles. The load magnitude will be greater than 60% of the 1RM, with the goal of continually loading against heavy resistance. Participants will complete 4 sets of 6 repetitions, with 3-5 minutes of rest between sets. Time under tension will be prescribed as \<1 second for the concentric phase and 1 second for the eccentric phase of the exercise. The strength training sessions will adhere to same parameters as the SOC. Hip abductor, hip extensor, and core exercises will be initiated during week 1 and continued for the 6-week intervention, while quadriceps focused exercises will be introduced in weeks 3-6.
Group II: Standard of Care (SOC)Active Control1 Intervention
The SOC rehabilitation group will complete three strength sessions a week. All participants will be provided an educational pamphlet and exercises will be divided into four components - hip abductors, hip extensors, core, and quadriceps muscles. The load magnitude for exercises will be between 60-70% of their 1 repetition max (1RM), with 3 sets of 12 repetitions and a 2-3-minute rest between sets. Time under tension will be prescribed as slow to moderate, with a 2-second concentric phase and 2-second eccentric phase for each exercise. Hip abductor, hip extensor, and core exercises will be initiated during week 1 and continued for the 6-week intervention, while quadriceps focused exercises will be introduced in weeks 3-6.
Research Highlights
Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.Mechanism Of Action
Side Effect Profile
Prior Approvals
Other Research
The most common treatments for Patellofemoral Pain Syndrome (PFPS) include strength training and power exercises. Strength training focuses on enhancing the strength of the quadriceps and hip muscles, which helps stabilize the patella and alleviate pain.
Power exercises involve rapid, forceful movements that improve muscle power and neuromuscular control, further aiding in patellar stability. These treatments are essential for PFPS patients as they correct muscle imbalances and biomechanical issues, leading to reduced pain and improved functional outcomes.
Find a Location
Who is running the clinical trial?
University of ConnecticutLead Sponsor
188 Previous Clinical Trials
160,233 Total Patients Enrolled
University of Central FloridaOTHER
90 Previous Clinical Trials
1,119,597 Total Patients Enrolled
University of ToledoOTHER
7 Previous Clinical Trials
654 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I have had issues with my kneecap, meniscus, or ligaments.I am between 18 and 40 years old.My symptoms started slowly over more than 3 months ago.I have had surgery on my leg or foot.My worst pain was 3/10 last month when sitting long, jumping, squatting, kneeling, running, or using stairs.I have experienced pain that spreads from my lower back.I have a different type of knee pain, not just PFPS.
Research Study Groups:
This trial has the following groups:- Group 1: Strength Training Rehabilitation Incorporating Power Exercises (STRIPE)
- Group 2: Standard of Care (SOC)
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
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