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Diazoxide for Type 2 Diabetes
Study Summary
This trial looks at the effects of diazoxide on the brain and how it regulates glucose production by the liver in people with type 2 diabetes.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- Your blood sugar levels are normal when fasting and over time.You smoke more than 10 cigarettes a day.You have a significant change in your white blood cell count.I have a blood clotting disorder.I do not have chronic liver, kidney diseases, HIV/AIDS, active cancer, heart disease, rheumatic conditions, seizures, bleeding or muscle disorders.I have had surgery to remove an endocrine gland, but not my thyroid.You have mental health conditions that are not being managed.I am experiencing extreme thirst and urination.I am 21-70 years old, have a BMI under 35, no drug use, normal blood sugar levels, and no close family with diabetes.A family member had a heart-related death at a young age.My immediate family does not have a history of diabetes.I do not have severe eye, kidney, or nerve problems related to diabetes.I have serious liver problems.I am between 21 and 70 years old.You have drugs in your system as shown by a urine test.You have a high level of protein in your urine, which may be a sign of diabetes.I have been diagnosed with severe anemia.If you have type 2 diabetes, you must be between 21 and 70 years old, have a body mass index under 35, and have a certain range of A1c levels. You should also not have certain eye, kidney, or nerve problems related to diabetes.You have a significant issue with your blood platelets.I have serious kidney problems.Your urine test shows important problems.I drink less than the maximum daily and weekly alcohol limits.Your A1c blood sugar level is between 8.0% and 12.0%.I am either younger than 21 or older than 70.My cholesterol levels are very high and not under control.You have important problems with the minerals in your body.I have passed a drug test recently.My BMI is over 35.Your blood pressure is consistently too high or too low.You have a body mass index (BMI) lower than 35.
- Group 1: T2D (Nicotinic Acid + placebo for diazoxide)
- Group 2: Non-diabetic (Diazoxide)
- Group 3: Non-diabetic (Placebo)
- Group 4: T2D (Diazoxide + Nicotinic Acid)
- Group 5: T2D (Placebo)
- Group 6: T2D (Diazoxide)
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How can I become a participant in this research?
"Eligibility criteria for this trial include being between 21 and 70 years old as well as having hyperglycemia. Currently, the study is looking to recruit 30 more individuals."
What medical conditions are typically treated with Diazoxide?
"Diazoxide is most often used to mitigate cardiovascular risks but can also be employed to lower the risk of pancreatitis and lipidemia or to treat dyslipidemias."
Are new volunteers still being sought for this experiment?
"The clinical trial is currently ongoing, with the most recent update being on June 15th, 2022. The study was initially posted on August 1st, 2018."
How many people are being signed up for this experiment?
"That is correct, the clinicaltrials.gov webpage for this research indicates that it is actively looking for patients. This study was originally posted on August 1st, 2018 and was last updated on June 15th, 2022. The ideal candidate pool consists of 30 individuals who are willing to travel to a single location."
Does this research study have an age limit?
"The eligibility requirements for this clinical trial state that patients between the ages of 21 and 70 may apply. There are 86 other trials available for minors and 899 options for seniors."
Has Diazoxide been federally authorized for medical use?
"While there is some evidence supporting Diazoxide's safety, it remains unproven whether or not the drug is actually effective. Therefore, it received a score of 2."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
How responsive is this trial?
Average response time
- < 2 Days
Typically responds via
Most responsive sites:
- Albert Einstein College of Medicine: < 48 hours
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