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DSC-MRI for Recurrent Glioblastoma
Study Summary
This trial uses DSC-MRI to measure rCBV to determine response to bevacizumab in patients with recurrent glioblastoma. DSC-MRI may help to evaluate changes in cancer blood vessels.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have never received immunotherapy treatments.My kidneys work well (eGFR >= 40).My weight is within the limit for an MRI scanner table.I am scheduled for treatment with a standard dose of bevacizumab.I am not taking bevacizumab for reasons unrelated to cancer treatment.My initial surgery confirmed I have glioblastoma or gliosarcoma.I am able to care for myself but may not be able to do active work.My brain tumor has grown despite treatment, and I am planned to receive bevacizumab.I can undergo MRI scans with contrast.I can have a small needle placed in my vein for treatment.I can safely receive IV contrast.I am not pregnant or breastfeeding.My low-grade brain tumor has transformed into a high-grade tumor.
- Group 1: Diagnostic (DSC-MRI)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many individuals are being enrolled in the study?
"For the successful completion of this clinical trial, 146 volunteers who match the pre-set inclusion criteria must join. The medical research is being carried out in various places including Washington University School of Medicine in Saint Louis, Arizona and Saint Joseph's Hospital and Medical Center in Phoenix, California."
Are there still openings for participants in this investigation?
"Clinicaltrials.gov affirms that recruitment for this trial is currently underway, with the initial posting taking place on April 14th 2017 and a subsequent update being made June 8th 2022."
Are there various sites conducting this scientific experiment in the same state?
"This trial is being conducted in conjunction with Washington University School of Medicine (St. Louis, MO), Saint Joseph's Hospital and Medical Center (Phoenix, AZ), Loma Linda University Medical Centre (Loma Linda, CA) as well as 47 other sites nationwide."
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