FES for Tremor Suppression
(Tremor Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial uses ultrasound imaging to study and understand hand tremors. It aims to help people with tremor disorders by accurately identifying involuntary muscle movements. The study includes both people with tremors and those without.
Do I need to stop my current medications for the trial?
The trial does not specify if you need to stop your current medications, but it excludes those using medications that affect the neuromuscular junction. It's best to discuss your specific medications with the trial coordinators.
Is functional electrical stimulation (FES) safe for humans?
Research on functional electrical stimulation (FES) for tremor suppression shows it can be used safely in humans, with studies indicating it effectively reduces tremors in conditions like essential tremor and Parkinson's disease. However, there are practical limitations, such as controlling only one pair of muscles at a time, which may restrict its use to certain types of tremors.12345
How does the FES treatment for tremor suppression differ from other treatments?
FES (Functional Electrical Stimulation) is unique because it uses electrical impulses to stimulate muscles, which can help suppress tremors by enabling controlled muscle movements. Unlike other treatments that might rely on medication or surgery, FES directly targets muscle activity and can be adjusted in real-time to manage muscle fatigue, making it a non-invasive and adaptable option for tremor management.678910
What data supports the effectiveness of the treatment for tremor suppression using ultrasound imaging and electrical stimulation?
Research shows that ultrasound imaging can effectively visualize muscle activity and changes, which helps in monitoring and adjusting electrical stimulation for muscle strengthening and motor restoration. This suggests that combining ultrasound with electrical stimulation could be beneficial for controlling tremors by providing real-time feedback and personalized treatment adjustments.6781112
Are You a Good Fit for This Trial?
This trial is for people aged 40-90 with Parkinson's Disease or tremor conditions, who have a rest tremor in their upper extremities. The tremor must be significant and re-emergent when holding a posture. Participants should not have other neuromuscular disorders, essential tremor, be on certain medications, or have muscle weakness.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo ultrasound imaging and functional electrical stimulation to analyze and suppress tremors
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation
- Electromyography
- Functional Electrical Stimulation (FES)
- Inertial Measurement Units (IMU)
- Ultrasound Imaging
Find a Clinic Near You
Who Is Running the Clinical Trial?
North Carolina State University
Lead Sponsor
University of North Carolina, Chapel Hill
Collaborator