Functional Electrical Stimulation (FES) for Familial Tremor

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Familial Tremor+2 More
Functional Electrical Stimulation (FES) - Device
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will focus on using ultrasound imaging to help detect, characterize, and differentiate tremors from voluntary hand motion in order to help design future functional electrical stimulation (FES)-based tremor-suppression techniques.

Eligible Conditions
  • Familial Tremor
  • Parkinson Disease

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

3 Primary · 0 Secondary · Reporting Duration: Through Completion of Study, an average of 3 years

Year 3
Tremor Model
Tremor Suppression
Ultrasound Imaging Based Frequency Detection

Trial Safety

Trial Design

2 Treatment Groups

Tremor Group
1 of 2
Able Body Group
1 of 2
Experimental Treatment

16 Total Participants · 2 Treatment Groups

Primary Treatment: Functional Electrical Stimulation (FES) · No Placebo Group · N/A

Tremor GroupExperimental Group · 4 Interventions: Ultrasound Imaging, Electromyography, Inertial Measurement Units (IMU), Functional Electrical Stimulation (FES) · Intervention Types: Device, Device, Device, Device
Able Body GroupExperimental Group · 4 Interventions: Ultrasound Imaging, Electromyography, Inertial Measurement Units (IMU), Functional Electrical Stimulation (FES) · Intervention Types: Device, Device, Device, Device
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ultrasound Imaging
2018
Completed Phase 4
~670
Electromyography
2018
N/A
~210
Functional Electrical Stimulation (FES)
2017
N/A
~100

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: through completion of study, an average of 3 years

Who is running the clinical trial?

North Carolina State UniversityLead Sponsor
27 Previous Clinical Trials
5,927 Total Patients Enrolled
University of North Carolina, Chapel HillOTHER
1,359 Previous Clinical Trials
3,927,052 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 5 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
Tremor amplitude must be at minimum 1 cm as determined by expert opinion by a movement disorders specialist.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 25th, 2021

Last Reviewed: October 13th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.