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Pain Sensitivity Assessment During Puberty for Pain

N/A
Recruiting
Led By Hadas Nahman-Averbuch, PhD
Research Sponsored by Washington University School of Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Aged 9-16 years old
English speakers
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 years
Awards & highlights

Study Summary

This trialstudies pain sensitivity in adolescents during puberty and its relation to sex hormone levels and chronic pain risk.

Who is the study for?
This trial is for healthy boys and girls aged 9-16 who speak English. It's not for those who are pregnant, have chronic pain or frequent headaches, psychiatric or neurological issues, sensation loss in limbs to be tested, conditions affecting puberty, or take regular pain meds.Check my eligibility
What is being tested?
The study tests how sensitive kids at different stages of puberty are to pain using various methods like heat and pressure. It looks at whether hormone levels affect this sensitivity and if changes during puberty might predict future chronic pain risk.See study design
What are the potential side effects?
Since the trial involves non-invasive testing rather than medication or surgery, side effects may include temporary discomfort from the sensory tests such as mild soreness or irritation where pressure or thermal stimuli were applied.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 9 and 16 years old.
Select...
I speak English.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Conditioned pain modulation
Pain ratings for cold stimuli
Pain ratings for heat stimuli
+1 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Psychophysical assessments of experimental painExperimental Treatment10 Interventions
At baseline, participants will complete a 2.5-hours study session. In the study session, psychophysical assessments of thermal and pressure stimuli will be performed and sex hormone levels will be analyzed. In addition, demographic, social, pubertal maturation, behavioral and psychological factors will be collected via questionnaires. In the optional follow-up portion, participants can complete short surveys every 3 months and/or return for study visits every year depending on the participant's availability. The study visits will include the same procedures as the baseline study visit. Additional surveys regarding new symptoms of pain will be completed. In some cases, participants will meet a pediatric physician who will determine if they meet the criteria for any pain syndrome (for research purposes only).

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Who is running the clinical trial?

Washington University School of MedicineLead Sponsor
1,928 Previous Clinical Trials
2,296,764 Total Patients Enrolled
13 Trials studying Pain
1,937 Patients Enrolled for Pain
Hadas Nahman-Averbuch, PhDPrincipal InvestigatorWashington University School of Medicine
3 Previous Clinical Trials
470 Total Patients Enrolled

Media Library

Psychophysical assessments of experimental pain Clinical Trial Eligibility Overview. Trial Name: NCT05145595 — N/A
Pain Research Study Groups: Psychophysical assessments of experimental pain
Pain Clinical Trial 2023: Psychophysical assessments of experimental pain Highlights & Side Effects. Trial Name: NCT05145595 — N/A
Psychophysical assessments of experimental pain 2023 Treatment Timeline for Medical Study. Trial Name: NCT05145595 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants will this clinical trial allow in total?

"Affirmative, the information available on clinicaltrials.gov attests that this study is currently accepting new participants. It was first listed on September 20th 2022 and its details were last revised November 28th of the same year. The trial requires 200 individuals to be enrolled from a single site."

Answered by AI

Is the age of admittance to this study limited to those younger than 45?

"Those wishing to be included in this clinical trial must fall into the age bracket of 9-16 years old. As for minors, 150 are expected to join while 404 seniors will participate."

Answered by AI

Can I qualify to be a subject in this experiment?

"200 individuals between the ages 9 and 16, who experience pain are eligible to participate in this clinical trial."

Answered by AI

Is it possible to still participate in the experiment?

"Yes, the trial is still actively recruiting. Clinicaltrials.gov records indicate that this study was initially made available to participants on September 20th 2022 and subsequently edited on November 28th of the same year."

Answered by AI
~128 spots leftby Dec 2026