SPG Nerve Block for Postoperative Pain
Trial Summary
Do I have to stop taking my current medications for the trial?
The trial information does not specify if you need to stop taking your current medications. However, if you have been using opioids regularly in the past 3 months, you would not be eligible to participate.
What data supports the effectiveness of the drug Dexamethasone when used with Ropivacaine for postoperative pain relief?
Is the SPG Nerve Block treatment safe for humans?
How does the SPG nerve block treatment for postoperative pain differ from other treatments?
The SPG (sphenopalatine ganglion) nerve block is unique because it targets a specific nerve cluster in the face to manage pain, which is different from other treatments that may use general pain relief methods. This approach can provide targeted pain relief with potentially fewer side effects compared to systemic pain medications.346810
What is the purpose of this trial?
Maxillary nerve blocks have been shown to significantly reduce post-operative pain and analgesic intake during the 24-hour period following sinus surgery. This randomized, double-blinded, placebo-controlled study will investigate blocks of the pterygopalatine fossa using a suprazygomatic approach during septorhinoplasty surgery. It is the investigator's hypothesis that this technique will result in decreased post-operative pain and opioid use, and the morbidity associated with it.
Research Team
Jeffrey D Johnson, MD
Principal Investigator
University of Florida
Eligibility Criteria
This trial is for adults aged 18-80 who are undergoing septorhinoplasty, can eat and drink normally before surgery, and have a physical status classified as ASA 1-3. It's not for those allergic to opioids, with chronic pain or ongoing opioid use, needing additional surgeries, pregnant women, without mobile texting capabilities, or deemed unsuitable by the study team.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo septorhinoplasty surgery with either Ropivacaine plus Dexamethasone or Placebo plus Dexamethasone administered via a suprazygomatic approach
Post-operative Monitoring
Participants are monitored for post-operative pain and opioid use reduction
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Dexamethasone
- Placebo
- Ropivacaine
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Florida
Lead Sponsor