Mindfulness of Pain for Depression

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Utah, Salt Lake City, UT
Depression+2 More
Mindfulness of Pain - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This will be a single-site, five-arm, parallel group randomized control trial involving patients undergoing knee or hip replacement surgery. The investigators will compare five different styles of 5-minute, audio-recoded mindfulness practices delivered via app 7 days before to surgery, 2 days before to surgery, 2 days after surgery, and 6 days after surgery.

Eligible Conditions

  • Depression
  • Pain
  • Anxiety

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 2 Secondary · Reporting Duration: During the 6 weeks prior to surgery and at the 6-week outpatient follow-up appointment

Week 6
Postoperative Patient Reported Outcomes Measurement Information System (PROMIS) Physical Functioning Item Bank, v2.0
Immediately before to after 5-minute audio recording
Change in Anxiety
Change in Depression
Change in Pain Intensity
Change in Pain Medication Desire
Change in Pain Unpleasantness

Trial Safety

Trial Design

5 Treatment Groups

Breath Counting
1 of 5
Mindful Savoring
1 of 5
Body Scan
1 of 5
Mindfulness of Pain
1 of 5
Mindful Breathing
1 of 5
Active Control
Experimental Treatment

305 Total Participants · 5 Treatment Groups

Primary Treatment: Mindfulness of Pain · No Placebo Group · N/A

Mindful Savoring
Behavioral
Experimental Group · 1 Intervention: Mindful Savoring · Intervention Types: Behavioral
Body Scan
Behavioral
Experimental Group · 1 Intervention: Body Scan · Intervention Types: Behavioral
Mindfulness of Pain
Behavioral
Experimental Group · 1 Intervention: Mindfulness of Pain · Intervention Types: Behavioral
Mindful Breathing
Behavioral
Experimental Group · 1 Intervention: Mindful Breathing · Intervention Types: Behavioral
Breath Counting
Behavioral
ActiveComparator Group · 1 Intervention: Breath Counting · Intervention Types: Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Mindfulness of Pain
2019
N/A
~120
Mindful Breathing
2019
N/A
~160

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: during the 6 weeks prior to surgery and at the 6-week outpatient follow-up appointment
Closest Location: University of Utah · Salt Lake City, UT
Photo of ut university of utah 1Photo of ut university of utah 2Photo of ut university of utah 3
2006First Recorded Clinical Trial
15 TrialsResearching Depression
673 CompletedClinical Trials

Who is running the clinical trial?

University of UtahLead Sponsor
976 Previous Clinical Trials
1,765,204 Total Patients Enrolled
17 Trials studying Depression
1,983 Patients Enrolled for Depression

Eligibility Criteria

Age 18+ · All Participants · 2 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are scheduled to undergo total joint arthroplasty of the knee or hip.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.