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Operant Conditioning of Cutaneous Reflexes for Neuropathic Pain

Medical University of South Carolina, Charleston, SC
Neuropathic Pain+3 More ConditionsOperant Conditioning of Cutaneous Reflexes - Behavioral
Eligibility
18+
All Sexes

Study Summary

This trial will study the effects of reflex training on reducing neuropathic pain in people who have spinal cord injuries. 15 participants will be recruited for 6.5 months of visits.

Eligible Conditions
  • Neurotrauma
  • Neuropathic Pain
  • Pain
  • Spinal Cord Injury

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
N/A

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Study Objectives

5 Primary · 4 Secondary · Reporting Duration: Completed at baseline, start of conditioning visits 13, 19, and 25, after completing 30 conditioning sessions, 1 month follow up, and 3 months follow up

Month 3
Change in basic functional independence as measured by the Spinal Cord Independence Measure (SCIM III)
Change in functional independence as measured by the Functional Independence Measure (FIM)
Change in quality of life as measured by Spinal Cord Injury Quality of Life and Participation Questionnaire (SCI-QOL)
Month 3
Change in ability to perceive various types of sensations as indicated by Quantitative Sensory Testing (QST)
Change in neuropathic pain as measured by the Neuropathic Pain Symptom Inventory (NPSI)
Change in pain as measured by the McGill Pain Questionnaire (MPQ)
Month 3
Change in minimum intensity at which the sensation covers the maximum area of skin (radiating threshold, RT)
Change in minimum intensity at which the stimulus become painful (pain threshold, PainT)
Change in minimum stimulation intensity required to barely detect the sensation (perceived threshold, perT)

Trial Safety

Phase-Based Safety

1 of 3

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2
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3
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Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

1 Treatment Group

Operant Conditioning of Cutaneous Reflexes
1 of 1

Experimental Treatment

15 Total Participants · 1 Treatment Group

Primary Treatment: Operant Conditioning of Cutaneous Reflexes · No Placebo Group · N/A

Operant Conditioning of Cutaneous Reflexes
Behavioral
Experimental Group · 1 Intervention: Operant Conditioning of Cutaneous Reflexes · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: completed at baseline, start of conditioning visits 13, 19, and 25, after completing 30 conditioning sessions, 1 month follow up, and 3 months follow up

Who is running the clinical trial?

Medical University of South CarolinaLead Sponsor
871 Previous Clinical Trials
5,368,865 Total Patients Enrolled
1 Trials studying Neuropathic Pain
Aiko Thompson, PhDPrincipal InvestigatorMedical University of South Carolina
1 Previous Clinical Trials
25 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have had a spinal cord injury over a year ago and your neurological condition has been stable since then.
If you have nerve pain, it must be in your lower leg.
References

Frequently Asked Questions

How many participants are included in this medical trial?

"Affirmative. The clinicaltrials.gov portal indicates that this research trial commenced on March 27th 2023 and is still actively recruiting participants. 15 individuals are sought from a single location to take part in the experiment." - Anonymous Online Contributor

Unverified Answer

Are there any vacancies available for individuals to join this trial?

"Affirmative, according to the information hosted on clinicaltrials.gov this medical trial is currently searching for participants. It was initially posted online on March 27th 2023 and last updated April 3rd 2023. 15 individuals are required at a singular test site." - Anonymous Online Contributor

Unverified Answer

What end results are expected from this research endeavor?

"The primary purpose of this trial is to observe the modification in pain threshold (PainT) from baseline till completion of training protocol, 1 month follow-up and 3 months follow-up. Additional secondary goals include tracking any changes in quality of life with Spinal Cord Injury Quality of Life and Participation Questionnaire (SCI-QOL), basic functional independence as per Spinal Cord Independence Measure (SCIM III) and Functional Independence Measure (FIM). SCI-QOL comprises 6 self care items with a subscore ranging between 0 - 20; 4 respiration & sphincter management items having subscore range 0 - 40" - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

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