Reviewed by Michael Gill, B. Sc.
25 Copd Clinical Trials Near Me
Top Hospitals for Copd Clinical Trials
Image of Research Site in California.
Research Site
Newport Beach
4Active Trials
6All Time Trials for Copd
2014First Copd Trial
Image of Research Site in Florida.
Research Site
Tampa
4Active Trials
12All Time Trials for Copd
2005First Copd Trial
Top Treatments for Copd Clinical Trials
Treatment Name
Active Copd Clinical Trials
All Time Trials for Copd
First Recorded Copd Trial
Inhaled treprostinil solution
2
2
2018
Tozorakimab
2
2
2022
Itepekimab SAR440340
2
3
2020
E-Cigarette
1
1
2022
Healthy Control Group
1
1
2023
Recently Completed Studies with FDA Approved Treatments for Copd
Treatment
Year
Sponsor
CSJ117
2021
Novartis Pharmaceuticals
Lemborexant 10 mg
2020
Eisai Inc.
Ensifentrine
2020
Verona Pharma plc
Belimumab
2018
University of Alabama at Birmingham

What Are COPD Clinical Trials?

COPD, or chronic obstructive pulmonary disease, is a group of chronic diseases that cause breathing and airflow-related issues, such as a blockage. COPD includes chronic bronchitis and emphysema. Symptoms of COPD include shortness of breath, coughing, wheezing, excessive mucus production, and chest tightness. Millions around the world suffer from COPD.

It essentially destroys the tissues in the area where oxygen is exchanged, causing less air to flow in and out of your lungs, making it harder to get oxygen and eliminate carbon dioxide from the body. As COPD worsens, it causes shortness of breath, making it challenging to maintain an active lifestyle.

Even though COPD is a chronic disease, people can enter COPD clinical trials. This way, these individuals get the opportunity to access new medical approaches, drugs, and better therapies targeted at treating, screening for, and preventing COPD. It gives people a chance to contribute to the understanding of this disease and stem its progression while getting the latest care from clinical experts.

Why Is COPD Being Studied Through Clinical Trials?

According to American Lung Association, COPD is a leading cause of disability and fatality in the U.S. Over 12.5 million Americans have been diagnosed with this disease, and millions yet may have COPD without even knowing it. This disease causes severe long-term disability and early death. Currently, there is no successful cure for COPD, and it is causing more deaths as more and more people are diagnosed with it.

COPD clinical trials enable specialists to learn more about this disease and discover possible treatment plans. New pulmonology-related researches and clinical trials test new drugs, interventions, surgical approaches, screening methods, and other treatments for early screening, prevention, and treatment of COPD.

What Are The Types of Treatments Available for COPD?

While there is no cure for COPD, multiple treatment options can help patients manage this disease. Depending on how advanced the patient’s symptoms are, their doctor might prescribe COPD medications to control their exacerbation, enable better breathing, and offer pulmonary rehabilitation, including exercise, knowledge, training, counseling, and more.

Some patients with COPD are also given supplemental oxygen. Endobronchial valve treatment is also provided to reduce lung hyperinflation. Lastly, doctors can prescribe lung surgery for patients with severe COPD symptoms to improve their breathing. Moreover, pulmonologists are involved in COPD clinical trials to discover new treatment options for this disease.

What Are Some Recent Breakthrough Clinical Trials for COPD?

There have been multiple COPD clinical trials in recent times. Here are the most notable ones:

2007-2022: Examining the Genetic Factors That May Cause COPD – This ongoing trial has spanned over a decade. Its purpose is to analyze DNA from former and current cigarette smokers to identify possible genetic markers and factors that might indicate a predisposition to COPD.

2021: A Review of Clinical Trials That Contributed to COPD Treatment Protocols – This review is essential to future COPD treatment as it comprehensively reviews significant studies from 2000 to 2020 that helped develop treatment protocols for COPD. It will also help researchers connect the dots to create updated COPD management guidelines and use salient features of previous studies in future trials to reduce mortality and morbidity of COPD.

Who Are Some of the Key Opinion Leaders / Researchers / Institutions Conducting COPD Trial Research?

Airways Clinical Research Center (ACRC)

Airways Clinical Research Centers Network is the crown jewel of the American Lung Association research program. It’s America’s largest non-profit network of clinical centers devoted to COPD and asthma research. Many experts work together under ACRC to conduct patient-focused clinical trials. In its analysis stage, a recent COPD clinical trial by ACRC is exploring the relationship between anxiety and COPD health status and prognosis to inform appropriate care strategies.

Verona

Verona is a clinical-stage biopharmaceutical company focusing on creating treatments for respiratory diseases, including COPD. It’s currently conducting an ongoing phase 3 ENHANCE-2 clinical trial of ensifentrine, used to treat COPD. The trial is showing positive results for ensifentrine use to reduce exacerbations.

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 7th, 2021

Last Reviewed: November 6th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

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