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TLD for COPD (AIRFLOW-3 Trial)
AIRFLOW-3 Trial Summary
This trial is testing a new device to treat COPD. The device is safe and effective.
AIRFLOW-3 Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowAIRFLOW-3 Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.AIRFLOW-3 Trial Design
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Who is running the clinical trial?
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- I have been diagnosed with high blood pressure in the lungs.I had a lung or chest surgery less than a year ago, with any metal placed at least 5cm away from where I'll be treated.I have COPD with specific lung function test results.I can stop taking blood thinners for a lung exam.I am 40 years old or older.You are not currently smoking or using any other inhaled substance (e.g., cigarettes, vaping, cannabis, pipes) for a minimum of 2 months prior to consent and agrees to not start for the duration of the study.I have severe stomach or swallowing problems.I am not pregnant or breastfeeding and agree not to become pregnant during the study.I have a lung condition not related to COPD that is the main cause of my symptoms.I have asthma according to the latest GINA guidelines.I don't have any health issues that could stop me from completing this study.I am taking more than 10 mg of prednisone or its equivalent daily.I am allergic to common anesthesia or bronchoscopy drugs that can't be managed.My CT scan shows severe lung issues or a mass needing treatment that can't be addressed with standard catheters.Your diabetes is not well managed, according to the doctor.I have had 2 or more moderate or at least 1 severe COPD flare-ups in the last year despite being on optimal medication.I take more than 40 mg of opioid medication daily.I have had 2 or more moderate or at least 1 severe COPD flare-ups in the last year despite being on optimal medication.I am not pregnant or breastfeeding and agree to avoid pregnancy during the study.I finished a lung rehab program over 3 months ago or will continue my current program.I have signed a consent form approved by the ethics committee.I've had cancer treatment with radiation or chemotherapy in the last year.Your body weight is either too low or too high for this study.I am 40 years old or older.I have had a flu shot in the last year or agree to get one and continue annually during the study.I agree to follow all study requirements, including tests and taking specific medications.I haven't had a severe heart attack or dangerous heart issues in the last 6 months.I had surgery on my stomach, esophagus, or pancreas within the last 2 years or have had related symptoms in the past year.You have smoked the equivalent of at least 10 packs of cigarettes over your lifetime.I have severe lung damage causing cough and thick mucus most days.You have smoked the equivalent of at least 10 packs of cigarettes in your lifetime.You have smoked the equivalent of 10 packs of cigarettes a year for at least one year.
- Group 1: Sham Control
- Group 2: Active Treatment
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many people are currently enrolled in this experiment?
"To satisfy the set parameters of this trial, 480 eligible patients must take part. These individuals will be sourced from two particular medical centres, namely University of Michigan in Ann Arbor and HonorHealth in Phoenix."
Is the clinical trial available at a variety of locations within this city?
"This medical study is being conducted from the University of Michigan in Ann Arbor, HonorHealth in Phoenix, and Spectrum Health Medical Group in Grand Rapids. Additionally, 20 additional sites are also a part of this clinical trial."
Are there opportunities for patients to enroll in this clinical trial currently?
"According to the records available on clinicaltrials.gov, this investigation has been open for recruitment since May 23rd 2019 and is up-to-date as of May 9th 2022."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
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