Gabapentin 300mg for Pain

Phase-Based Progress Estimates
3
Effectiveness
3
Safety
Pain+5 MoreGabapentin 300mg - Drug
Eligibility
18 - 65
All Sexes
What conditions do you have?
Select

Study Summary

This study is evaluating whether a combination of gabapentin and pregabalin can reduce the amount of opioid pain medication used in orthopedic trauma patients.

Eligible Conditions
  • Pain
  • Trauma
  • Narcotics
  • Injury
  • Painkillers
  • Gabapentin

Treatment Effectiveness

Effectiveness Progress

3 of 3
This is further along than 93% of similar trials

Study Objectives

1 Primary · 5 Secondary · Reporting Duration: First 7 days post-enrolment or until discharge, if discharge < 7 days post-enrollment

Day 7
Hospital length of stay
Incentive spirometry values
Rate of intubation
Rate of unplanned ICU admission
Reduction in opioid usage
Day 7
Pain control

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

3 Treatment Groups

Neither Pregabalin nor Gabapentin
1 of 3
Gabapentin
1 of 3
Pregabalin
1 of 3

Active Control

Experimental Treatment

210 Total Participants · 3 Treatment Groups

Primary Treatment: Gabapentin 300mg · No Placebo Group · Phase 4

Gabapentin
Drug
Experimental Group · 1 Intervention: Gabapentin 300mg · Intervention Types: Drug
Pregabalin
Drug
Experimental Group · 1 Intervention: Pregabalin 50mg · Intervention Types: Drug
Neither Pregabalin nor Gabapentin
Drug
ActiveComparator Group · 1 Intervention: Neither Pregabalin nor Gabapentin · Intervention Types: Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Gabapentin
FDA approved
Pregabalin
FDA approved

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: first 7 days post-enrolment or until discharge, if discharge < 7 days post-enrollment

Who is running the clinical trial?

CAMC Health SystemLead Sponsor
44 Previous Clinical Trials
7,466 Total Patients Enrolled

Eligibility Criteria

Age 18 - 65 · All Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Hospitalization is projected to exceed 24 hours from the time of consent.
You are eligible for Nurse Practitioner service admittance.
You must be a minimum of 18 years old to participate.
Patients are enrolled within three-sixths of a day after admission.
You possess an active opioid prescription at the time of enrollment.