This trial studies olaparib with cediranib or AZD6738 as a treatment for patients with BRCA mutated breast cancer that has spread to other places in the body.
- Stage III Breast Cancer
- BRCA2 Gene Mutation
- BRCA1 Gene Mutation
- Stage IIIB Breast Cancer
- Metastatic Breast Cancer
- Stage IV Breast Cancer
- HER2/Neu Negative Breast Cancer
- Stage IIIA Breast Cancer
- Breast Cancer
1 Primary · 2 Secondary · Reporting Duration: Up to 30 days post treatment
Side Effects for
Awards & Highlights
2 Treatment Groups
Arm II (olaparib plus ceralasertib)
1 of 2
Arm I (olaparib plus cediranib)
1 of 2
60 Total Participants · 2 Treatment Groups
Primary Treatment: Olaparib · No Placebo Group · Phase 2
Who is running the clinical trial?
Age 18+ · Female Participants · 2 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
Are more participants needed for this experiment at the present time?
"Indeed, clinicaltrials.gov reveals that this medical experiment is actively accepting participants. It was initially posted on July 28th 2020 and updated as recently as March 31st 2022. Approximately 60 individuals are expected to be recruited from a single site." - Anonymous Online Contributor
What is the current capacity for enrolment in this research project?
"Indeed, the clinical trial data present on clinicialtrials.gov confirms that recruitment for this study is still ongoing. It was initially posted on July 28th 2020 and most recently updated in March 31st 2022, with a need to recruit 60 patients from 1 medical centre." - Anonymous Online Contributor
To what degree can Olaparib be considered a risk to human health?
"As this is a second-phase trial, there's evidence of Olaparib's safety making its score 2 out of 3. However, no data exists to support the drug's efficacy yet." - Anonymous Online Contributor
Could you elaborate on any additional research done with Olaparib?
"Olaparib is the subject of 204 active research trials, 27 which are in their final phase. While Houston, Texas houses many studies for this drug, there are over 9 thousand other locations running clinical trials on its efficacy." - Anonymous Online Contributor
Is this experiment the inaugural endeavor of its kind?
"Globally, there are 204 dynamic clinical trials involving the drug Olaparib being conducted across 59 countries and 1490 cities. The original trial for this medication began in 2005 when 98 participants took part in a Phase 1 Drug Approval study sponsored by AstraZeneca. Since then, 113 studies have been concluded." - Anonymous Online Contributor
What ailments is Olaparib typically prescribed to treat?
"Olaparib is a medication that can be prescribed to treat numerous conditions, ranging from advanced directives to malignant neoplasm of ovary and primary peritoneal cancer. It may also be administered for hallucinations and somatic problems." - Anonymous Online Contributor