Virtual Reality for Acute Pain in Children

HX
Overseen ByHenry Xiang, MD, MPH, PhD, MBA
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: Nationwide Children's Hospital
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to explore how virtual reality (VR) can reduce pain during medical procedures for children. Researchers will use a special brain imaging tool to study pain responses and relief as children engage in activities like playing a VR game or watching a VR video. The goal is to predict and enhance how VR manages pain. Children who are healthy, not currently experiencing pain, and understand English may be suitable for this trial. As an unphased trial, this study provides a unique opportunity for children to contribute to innovative research that could improve pain management techniques for future patients.

Will I have to stop taking my current medications?

The trial requires that participants have not taken any pain medication within the past 12 hours before participating.

What prior data suggests that Virtual Reality Pain Alleviation Therapy (VR-PAT) is safe for children?

Research shows that Virtual Reality for Pain Relief (VR-PAT) is generally safe for helping children manage sudden pain. Studies have found that VR effectively reduces pain during various medical procedures for kids and lowers their anxiety about these procedures. Most research indicates that VR is well-tolerated, with few reports of negative side effects.

Although VR is not yet widely used for pain management, existing studies highlight its safety and effectiveness. Many parents also feel positive about using VR to relieve their children's pain. Overall, VR-PAT appears to be a promising and safe method for managing pain in children.12345

Why are researchers excited about this trial?

Researchers are excited about Virtual Reality Pain Alleviation Therapy (VR-PAT) for acute pain in children because it offers a novel, non-invasive way to manage pain. Unlike traditional pain relief methods, which often rely on medications like acetaminophen or ibuprofen, VR-PAT uses immersive virtual reality experiences to distract and engage children, reducing their perception of pain. The active engagement in a VR game may enhance the pain relief effect compared to passive viewing or non-immersive platforms like an iPad. This innovative approach not only aims to minimize the need for medication but also makes pain management interactive and potentially more effective for kids.

What evidence suggests that Virtual Reality Pain Alleviation Therapy could be effective for acute pain in children?

This trial will compare different approaches to pain management in children using Virtual Reality Pain Alleviation Therapy (VR-PAT). Studies have shown that VR-PAT effectively reduces pain and anxiety in children. Research indicates that VR provides a safe, non-drug method for pain relief during medical procedures. Specifically, VR has been found to lower pain levels and help children focus less on their pain. Evidence suggests VR may outperform traditional methods like distraction and relaxation techniques. Overall, VR-PAT has shown promising results in reducing pain and stress for children in medical settings. Participants in this trial may experience different forms of VR-PAT, including active and passive VR experiences, or compare these to traditional methods like playing a game on an iPad.12678

Who Is on the Research Team?

HX

Henry Xiang, MD, MPH, PhD, MBA

Principal Investigator

Nationwide Children's Hospital

Are You a Good Fit for This Trial?

This trial is for healthy children who can participate in a study involving simulated pain and virtual reality. They will be part of an experiment to understand how the brain reacts to pain and if VR can help manage it.

Inclusion Criteria

I am between 6 and 17 years old.
Subjects and legal guardians can communicate (read and write) using English

Exclusion Criteria

I have a history of motion sickness, seizures, dizziness, or migraines triggered by visual auras.
I have taken pain medication in the last 12 hours.
Minors in foster care, incarcerated, or currently pregnant
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Experimental Session

Participants undergo a 1-hour research visit involving simulated pain and VR interventions

1 hour
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after the experimental session

1-2 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Virtual Reality Pain Alleviation Therapy (VR-PAT)
Trial Overview The study tests how different forms of distraction (an immersive VR game, a passive VR video, and playing on an iPad) affect the brain's response to simulated pain using fNIRS neuroimaging technology.
How Is the Trial Designed?
4Treatment groups
Experimental Treatment
Active Control
Group I: Active VR-PATExperimental Treatment1 Intervention
Group II: ControlActive Control1 Intervention
Group III: Passive VR-PATActive Control1 Intervention
Group IV: iPad gameActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Nationwide Children's Hospital

Lead Sponsor

Trials
354
Recruited
5,228,000+

Published Research Related to This Trial

The INOVATE-Pain consortium, consisting of 16 experts, aims to improve the use of virtual reality (VR) and augmented reality (AR) in treating pediatric chronic pain by establishing best practices for designing and evaluating these interventions.
Key recommendations include fostering partnerships among stakeholders, standardizing outcome measures for evaluation, and ensuring access to resources, all of which are essential for developing effective VR-based pain management solutions for children.
Leveraging Virtual Reality and Augmented Reality to Combat Chronic Pain in Youth: Position Paper From the Interdisciplinary Network on Virtual and Augmented Technologies for Pain Management.Logan, DE., Simons, LE., Caruso, TJ., et al.[2021]
A case study involving a 16-year-old patient with cerebral palsy showed that using virtual reality (VR) during physiotherapy sessions significantly reduced pain levels by 41.2% compared to sessions without VR.
This study suggests that VR can be an effective non-pharmacologic pain management strategy for children recovering from surgery, especially for those who may not tolerate traditional pain medications.
Virtual reality as a pediatric pain modulation technique: a case study.Steele, E., Grimmer, K., Thomas, B., et al.[2011]
In a case series involving 10 chronic pain patients, 5 reported reduced pain during virtual reality (VR) therapy sessions, suggesting potential short-term benefits of VR for pain management.
While VR therapy did not show significant overall changes in pain scores after treatment, it was safe with no serious adverse events, although 60% of participants experienced some cybersickness.
Virtual Reality as an Adjunct Home Therapy in Chronic Pain Management: An Exploratory Study.Garrett, B., Taverner, T., McDade, P.[2020]

Citations

Implementation of Virtual Reality Pain Alleviation ...... VR-PAT is a safe non-pharmacological pain alleviation therapeutic. While VR has been found safe and effective for acute pain alleviation during pediatric ...
Efficacy of virtual reality in pediatric burn patientsConclusion: Findings from this study indicate that VR has a positive effect on alleviating pain and reducing anxiety in pediatric patients with ...
Parents' Perspectives on the Use of Virtual Reality in ...More research is required to support the effectiveness of VR technologies for chronic pain management in children and adolescents.
Virtual reality for pain and anxiety management in children ...Conclusions. Evidence suggests VR may be more effective than traditional non-pharmacological pain and fear relief. This result seems to be consistent through ...
Virtual reality and pain management: current trends and future ...VR was found to decrease pain levels, anxiety and time spent thinking about pain. Das et al. conducted a randomized control trial, comparing standard of care ( ...
Virtual reality for pain management: an umbrella reviewThis umbrella review demonstrates successful application of virtual reality in pain control, including perioperative, periprocedural, and chronic pain settings.
Virtual reality in pediatrics, effects on pain and anxietyVirtual reality is a useful tool to reduce pain and anxiety in pediatric patients undergoing a range of medical procedures as it significantly decreases pain ...
What Features Make Virtual Reality Effective in Pain ...It was developed for pain alleviation during burn dressing changes by Nationwide Children's Research Information Solutions and Innovation ...
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