Complex Regional Pain Syndrome Clinical Trials 2022

Browse 9 Complex Regional Pain Syndrome Medical Studies Across 9 Cities

1 Phase 3 Trial · 10 Complex Regional Pain Syndrome Clinics

Reviewed by Michael Gill, B. Sc.
Phase-Based Progress Estimates
1
Effectiveness
1
Safety

Phase 1for Complex Regional Pain Syndrome (RSD)

West Haven, CT
18+
All Sexes
Objective: The primary aim is to evaluate the efficacy of botulinum toxin A in reducing overall limb pain in patients with complex regional pain syndrome (CRPS). Additionally the investigators would like to see if quality of life is improved and disability scores decreased. Research Design: This is a double blinded, randomized cross-over study that will be conducted over a 7 month period. It is a pilot study that will include twenty subjects recruited from the Neurology CRPS clinic at VA Connecticut and from outside VA hospitals within a 150 mile radius. Subjects will receive an intramuscular injection Treatment A which is only 1% lidocaine or Treatment B which is mixture of botulinum toxin A + 1% lidocaine in the affected limb only. This is a cross over study where patients will receive Treatment A or B initially during the first of four study visits and during the third study visit while receive whichever treatment not given during the first visit. Dr. Sameer Ali, VA neurology fellow, will be blinded when administering the treatments. Dr. Hajime Tokuno, VA neurologist who is the principal investigator of the trial will prepare the treatments. Clinical pharmacy will be randomizing the treatments. Dr. Tokuno will not be blinded as he needs to know which treatment has been given in case of complications. Impact/Significance: The significance of this study is the possible discovery of a new, safer, less invasive, and more efficacious therapeutic option for patients suffering from CRPS. Currently medical management with neuropathic pain meds, interventions such as sympathetic nerve blocks and ketamine infusion has helped some patients and not others. The investigators are trying to see whether either of the two treatments and especially the treatment with botulinum toxin may be a more viable alternative than existing modalities.
Phase < 1
Waitlist Available
9 Complex Regional Pain Syndrome Clinical Trials Near Me
Hamilton, Canada
Ottawa, Canada
Ottawa, Canada
Ann Arbor, MI
More Trial Locations
An interactive map to display trial locations for St. Joseph's Healthcare Hamilton King Campus, The Ottawa Hospital, Elisabeth Bruyere Hospital, University of Michigan, and 6 more locations.
Most Popular References for Complex Regional Pain Syndrome Clinical Trials
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Top Hospitals for Complex Regional Pain Syndrome Clinical Trials
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St. Joseph's Healthcare Hamilton King Campus, Hamilton, Ontario
1
1
2022
Elisabeth Bruyere Hospital, Ottawa, Ontario
1
2
2017
University of Michigan, Ann Arbor, Michigan
1
1
2021
University of California, San Francisco, San Francisco, California
1
1
2019
Top Treatments for Complex Regional Pain Syndrome Clinical Trials
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Active Complex Regional Pain Syndrome Clinical Trials
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Top Cities for Complex Regional Pain Syndrome Clinical Trials
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Trial List
Hamilton, Ontario
1
St. Joseph's Healthcare Hamilton King Campus
Ann Arbor, Michigan
1
University of Michigan
San Francisco, California
1
University of California, San Francisco
Cleveland, Ohio
1
Cleveland Clinic Pain Management
Which phases are most popular for complex regional pain syndrome clinical trials?
How many complex regional pain syndrome clinical trials are open to youth and / or seniors?
Phase 3 Complex Regional Pain Syndrome Clinical Trials
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Senior Friendly Complex Regional Pain Syndrome Clinical Trials

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 11th, 2021

Last Reviewed: August 6th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.