Complex Regional Pain Syndrome Clinical Trials 2023

Complex Regional Pain Syndrome Clinical Trials 2023

Complex Regional Pain Syndrome research studies recruiting patients in 2023 need your help. Receive premium care & cutting edge treatments by enrolling in complex regional pain syndrome clinical trials today.

Complex Regional Pain Syndrome Clinical Trials

Here are the 6 most popular medical studies for complex regional pain syndrome

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CRPS Clinical Trials

View 17 CRPS medical studies.

Chronic Pain Clinical Trials

View 7 Chronic Pain medical studies.

Complex Regional Pain Syndrome Clinical Trials With No Placebo

View 18 complex regional pain syndrome medical studies that do not have a placebo group.

West Haven, Connecticut

Neurotoxin

Botulinum Toxin Injection for Complex Regional Pain Syndrome

Recruiting2 awardsPhase < 1
West Haven, Connecticut

Objective: The primary aim is to evaluate the efficacy of botulinum toxin A in reducing overall limb pain in patients with complex regional pain syndrome (CRPS). Additionally the investigators would like to see if quality of life is improved and disability scores decreased. Research Design: This is a double blinded, randomized cross-over study that will be conducted over a 7 month period. It is a pilot study that will include twenty subjects recruited from the Neurology CRPS clinic at VA Connecticut and from outside VA hospitals within a 150 mile radius. Subjects will receive an intramuscular injection Treatment A which is only 1% lidocaine or Treatment B which is mixture of botulinum toxin A + 1% lidocaine in the affected limb only. This is a cross over study where patients will receive Treatment A or B initially during the first of four study visits and during the third study visit while receive whichever treatment not given during the first visit. Dr. Sameer Ali, VA neurology fellow, will be blinded when administering the treatments. Dr. Hajime Tokuno, VA neurologist who is the principal investigator of the trial will prepare the treatments. Clinical pharmacy will be randomizing the treatments. Dr. Tokuno will not be blinded as he needs to know which treatment has been given in case of complications. Impact/Significance: The significance of this study is the possible discovery of a new, safer, less invasive, and more efficacious therapeutic option for patients suffering from CRPS. Currently medical management with neuropathic pain meds, interventions such as sympathetic nerve blocks and ketamine infusion has helped some patients and not others. The investigators are trying to see whether either of the two treatments and especially the treatment with botulinum toxin may be a more viable alternative than existing modalities.

View More Complex Regional Pain Syndrome Trials

Another medical study focused on complex regional pain syndrome.

Frequently Asked Questions

Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.

Introduction to complex regional pain syndrome

What are the top hospitals conducting complex regional pain syndrome research?

Complex regional pain syndrome (CRPS) is a debilitating condition that affects a patient's nervous system, causing severe and chronic pain. In the quest for effective treatments and interventions, several top hospitals are leading the way in conducting clinical trials dedicated to CRPS. Stanford University, situated in Palo Alto and Stanford, has emerged as a frontrunner with its ongoing commitment to addressing this complex and challenging disorder. Currently, they have two active trials focused on CRPS, building upon their previous two studies since undertaking their initial trial in 2015. Meanwhile, the University of Washington in Seattle has made notable strides by exclusively offering clinical trials specifically tailored to CRPS patients; their dedication includes an ongoing trial and one previously conducted study starting from 2022.

Furthermore, groundbreaking efforts can be witnessed at the Fralin Biomedical Research Institute located in Roanoke where they are actively pursuing one trial targeting complex regional pain syndrome while also having completed another investigation since initiating research endeavors into this condition just last year—2023.Though relatively new to the field compared to other institutions mentioned here,the UCSF Medical Center based out of San Francisco showcases equal determination with its present-day engagement in an ongoing clinical trial alongside gainful utilization of opportunities provided by their past singular investigations beginning from 2022 onwards.

These hospitals' unwavering dedication towards advancing our understanding of CRPS demonstrates a commitment to improving the lives of those living with this excruciating condition. By pioneering innovative approaches through rigorous scientific investigations,collaborating across specialties,and employing cutting-edge technologies these institutions endeavor not only provide much-needed relief but also strive toward finding long-lasting solutions for a better quality life for individuals battling Complex Regional Pain Syndrome

Which are the best cities for complex regional pain syndrome clinical trials?

When it comes to clinical trials for complex regional pain syndrome, several cities are leading the way in research and treatment options. Palo Alto, California and San Francisco, California both have 2 active trials each, focusing on interventions such as Empowered Relief for Youth, LDN, High Frequency rTMS, Active DBS. Additionally, Stanford University in California has 1 active trial investigating treatments like Ketamine and Midazolam. Seattle in Washington also has 1 ongoing trial exploring Roosevelt "in Clinic VR" + "VR homeworks". Finally, Roanoke in Virginia offers 1 active trial studying LIFU - CRPS. These cities serve as hubs of innovation and provide individuals with complex regional pain syndrome access to cutting-edge clinical trials that offer hope for improved outcomes and relief from their condition.

Which are the top treatments for complex regional pain syndrome being explored in clinical trials?

Clinical trials exploring treatments for complex regional pain syndrome (CRPS) have identified two top contenders. First on the list is Empowered Relief for Youth, which has shown promise in its ongoing trial specifically targeting CRPS. Introduced in 2023, this treatment aims to provide relief and improvement for young patients suffering from this debilitating condition. Another contender making waves is High Frequency rTMS, with an active trial dedicated to investigating its effectiveness against CRPS. This innovative therapy was first listed in 2022 and holds potential as a non-invasive option for managing the symptoms of CRPS. As research progresses, these treatments offer hope for individuals living with the burdensome challenges of CRPS.

What are the most recent clinical trials for complex regional pain syndrome?

In the realm of complex regional pain syndrome (CRPS), recent clinical trials have focused on exploring the potential benefits of ketamine and midazolam. In a Phase 2 trial, these medications are being investigated for their effectiveness in alleviating the symptoms associated with CRPS. By targeting and managing the unique challenges posed by this condition, researchers aim to enhance patient outcomes and provide relief from chronic pain. With ongoing studies delving into innovative treatment approaches, there is hope for improved quality of life for individuals battling CRPS.

What complex regional pain syndrome clinical trials were recently completed?

Recently completed clinical trials have made significant progress in the field of complex regional pain syndrome (CRPS). These trials aimed to enhance our understanding and develop improved treatments for this debilitating condition. One notable trial was sponsored by the National Institute of Neurological Disorders and Stroke, which explored new therapeutic approaches and concluded recently. Another important study, conducted by Johns Hopkins University School of Medicine, examined the effectiveness of a novel intervention technique on CRPS symptoms. These successful advancements offer hope to individuals living with CRPS and highlight the ongoing efforts to find better solutions for managing this challenging condition.