200 Participants Needed

Local Multimodal Analgesia vs Regional Anesthesia for Ankle Fracture

Recruiting at 1 trial location
Age: 18+
Sex: Any
Trial Phase: Phase < 1
Sponsor: University of Utah
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The investigators plan to evaluate the efficacy in reducing post-operative pain between local multimodal analgesia as compared to regional anesthesia in rotational ankle fractures.

Who Is on the Research Team?

JH

Justin Haller, MD

Principal Investigator

University of Utah Orthopaedics

Are You a Good Fit for This Trial?

This trial is for individuals with isolated rotational ankle fractures who need surgery, can give informed consent, and communicate in English or Spanish. It's not for those with drug dependency history, stroke, major neurological issues, other leg fractures, allergies to injection ingredients used in the study, head injuries or open fractures.

Inclusion Criteria

I need surgery for a broken ankle caused by twisting it.
Ability to provide informed consent
I can talk or email the research team.

Exclusion Criteria

I have a head injury along with my current condition.
Prior drug dependency
Allergies to any of the ingredients in the local injection or peripheral nerve block
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either local multimodal analgesia or regional anesthesia for pain management post-surgery

Immediate post-operative period
1 visit (in-person)

Follow-up

Participants are monitored for pain levels and narcotic usage at 1, 2, 4, 8, and 24 hours post-operatively

24 hours
Multiple assessments (in-person)

Extended Follow-up

Participants are monitored for pain levels and narcotic usage up to 8 weeks post-operatively

8 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Local Multimodal Analgesia
  • Regional Anesthesia
Trial Overview The study compares two pain control methods after ankle fracture surgery: one group receives local multimodal analgesia injections at the injury site; another gets regional anesthesia that numbs a larger area of the body.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Local multimodal analgesia groupExperimental Treatment1 Intervention
Group II: Regional anesthesia groupActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Utah

Lead Sponsor

Trials
1,169
Recruited
1,623,000+
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