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Non-invasive Brain Stimulation

TMS for Complex Regional Pain Syndrome

N/A

Recruiting

Research Sponsored by Stanford University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Average pain level reported on Numerical Rating Scale meets entry criteria

Age 18-70

Timeline

Screening 3 weeks

Treatment Varies

Follow Up duration from last treatment until pain returns - up to an estimate of 6 months

Awards & highlights

Study Summary

This trial is testing whether TMS can help with the Complex Regional Pain Syndrome (CRPS). It is hypothesized that those who receive TMS will have less pain and other symptoms than those who don't.

Who is the study for?

This trial is for adults aged 18-70 with Complex Regional Pain Syndrome (CRPS) for at least 3 months, who can perform required tasks and have a certain level of pain. It's not for those with psychological disorders, medical conditions or medications that affect the study, pregnant women, people in legal/disability claims, TMS contraindications like metal implants near stimulation site, epilepsy sufferers or those with MRI contraindications.Check my eligibility

What is being tested?

The trial tests if Transcranial Magnetic Stimulation (TMS) can reduce CRPS-related pain and improve cognitive, emotional and physical symptoms. Participants are divided into two groups: one receives TMS while the other gets sham treatment daily for two days. Their progress is monitored until they return to baseline pain levels for two weeks.See study design

What are the potential side effects?

While specific side effects of TMS in this trial aren't listed, common ones include discomfort at the stimulation site during treatment sessions, headache after treatment and rarely seizures.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My pain level matches the study's required range.

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I am between 18 and 70 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ duration from last treatment until pain returns - up to an estimate of 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~duration from last treatment until pain returns - up to an estimate of 6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and duration from last treatment until pain returns - up to an estimate of 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Pain

Duration of Pain Relief

Secondary outcome measures

Change in Pain-related Symptomology

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Active TreatmentExperimental Treatment1 Intervention

Participants will receive active TMS in the target area once daily for two days

Group II: Sham TreatmentPlacebo Group1 Intervention

Participants will receive active TMS in a non-target area once daily for two days

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Transcranial Magnetic Stimulation (TMS)

2018

Completed Phase 4

~570

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Stanford UniversityLead Sponsor

2,395 Previous Clinical Trials

17,341,315 Total Patients Enrolled

Rocky Mountain FoundationUNKNOWN

National Institutes of Health (NIH)NIH

2,701 Previous Clinical Trials

7,506,836 Total Patients Enrolled

Media Library

TMS (Non-invasive Brain Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT03137472 — N/A

Complex Regional Pain Syndrome Research Study Groups: Active Treatment, Sham Treatment

Complex Regional Pain Syndrome Clinical Trial 2023: TMS Highlights & Side Effects. Trial Name: NCT03137472 — N/A

TMS (Non-invasive Brain Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03137472 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can senior citizens above the age of 85 partake in this trial?

"Per the qualifications for participation, those aged 18-70 are eligible to enrol in this study."

Answered by AI

Does my profile meet the criteria for participating in this clinical experiment?

"Patients that between 18 and 70 years of age with complex regional pain syndromes, who are also capable of meeting the experimental requirements set out by this trial, will be accepted. Moreover, candidates must display an average level of pain as scored on a Numerical Rating Scale to qualify. Altogether 40 individuals may participate in this clinical investigation."

Answered by AI

Is enrollment in this study currently open?

"This research project, which was first advertised on the 24th of April 2017 and its latest update being the 8th June 2022, is still on the hunt for participants."

Answered by AI

What is the target enrollment size for this research project?

"Affirmative. Per the information hosted on clinicaltrials.gov, this medical examination is actively searching for volunteers to participate in it - with a total of 40 participants needing to be recruited from one site. It was first published online on April 24th 2017 and its most recent update occurred on June 8th 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

TMS for Complex Regional Pain Syndrome

Sean Mackey 2017. "TMS for Complex Regional Pain Syndrome". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03137472.

All > Complex Regional Pain Syndrome