Case Management and Peer Recovery for Opioid Abuse

High Risk
Recruiting · 18+ · All Sexes · Murphysboro, IL

This study is evaluating whether a program that helps people with opioid use disorder get into treatment can reduce opioid overdose deaths.

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About the trial for Opioid Abuse

Eligible Conditions
Opioid Use Disorder (OUD) · Opioid-Related Disorders · Opioids Use

Treatment Groups

This trial involves 2 different treatments. Case Management And Peer Recovery is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are not being studied for commercial purposes.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
Case Management and Peer Recovery
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.


This trial is for patients born any sex aged 18 and older. There are 3 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Participants must be at least 18 years old
Reside in designated research site county or zip code
Satisfy criteria for likely OUD based upon nonmedical use of prescription opioids, heroin, or synthetic opioids.
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Odds of Eligibility
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: 12 months
Screening: ~3 weeks
Treatment: Varies
Reporting: 12 months
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: 12 months.
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Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Case Management and Peer Recovery will improve 2 primary outcomes and 12 secondary outcomes in patients with Opioid Abuse. Measurement will happen over the course of 90 days.

Percent of participant utilizing mental health services
Defined as any mental health utilization within 90 days conditional on CAT-MH diagnostic.
Number (Percent) of participant utilizing mental health services
Defined as any mental health utilization within 90 days conditional on CAT-MH diagnostic.
Social cost of re-arrest and associated offenses
Total social cost of crime, using estimates for offense-specific economic valuations of social cost per offense and any charge using data from Illinois Criminal Justice Information Authority (ICJIA).
Social cost of self reported crime
Total social cost of self-reported illegal activity, using estimates for offense-specific economic valuations of social cost per offense and a self-reported count of 19 items across different types of illegal activities.
Re-arrest and Re-incarceration
Arrest or re-incarceration based on any charge using data from Illinois Criminal Justice Information Authority (ICJIA). The investigators will examine the binary outcomes of re-arrest and reincarceration, and also count data models of the number of arrests post-enrollment during days of non-incarceration.
Patient Reported Outcomes Measurement Information System
This scale of person-centered measures includes eight domains (physical function, ability to participate in social roles and activities, anxiety, depression, fatigue, sleep disturbance, cognitive function ability, pain interference, and pain intensity). These are elicited in a five point likert scale (from 1= never to 5 = always) with higher scores equaling more of the concept being measured, which may be better or worse based on the domain measured.
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Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are common treatments for opioid abuse?

Physicians and health services providers commonly give prescriptions for a variety of opioid medications to people to reduce opioid abuse. These medications include short-acting opioids (including hydrocodone), long-acting opioids (including heroin, methadone, and synthetic opiates), and a wide range of combinations. The effects of opioid use on health and well-being vary widely among individuals according to age, sex, ethnicity, baseline substance use history, mental and emotional health, disease status, and other factors.

Anonymous Patient Answer

What causes opioid abuse?

Abuse of opiates such as heroin and opiates which appear to have more convenient abuse profiles is more common than abuse of prescription opioids such as oxycodone or hydrocodone. In countries of the Western world, where prescription opioid use has increased rapidly, abuse of such drugs is a growing problem for health care. In countries such as Australia, where prescription opioids make up the majority of abuse, opioids account for most of the non-medical use of opiates. Prevention of abuse of prescription opioids has become a growing public health concern, particularly in the treatment of chronic pain.

Anonymous Patient Answer

How many people get opioid abuse a year in the United States?

There are about 9 million people in the United States who take prescription medication for chronic pain. At least 5 million of these, or 55%, use opioids annually by illicit, medical, or self-medication routes of administration. The proportion of opioid abusers who have used other forms of illicit prescription medication in the previous year has been increasing rapidly since the mid-1990s. While these trends are not consistent across races and ethnic groups, illicit opioids may be the most prevalent addictive agent currently available in the United States.

Anonymous Patient Answer

Can opioid abuse be cured?

It seems to be a complicated treatment. It is advisable to be a patient when seeing a psychiatrist and to follow the advice of family members and people who have had experience with rehabilitation. The treatment must be in cooperation with other health care doctors.

Anonymous Patient Answer

What are the signs of opioid abuse?

The frequency of opioid abusers in our Emergency Department was comparable to that reported by other studies of a similar population. As such, the signs of opioid abuse that clinicians should be aware of are not specific to this subset of patients, regardless of whether they have been using pharmaceutical analgesics. More broadly, our exploratory data suggests that opioid abusers may have more severe health problems than non-abusing opioid-using patients, and possibly more severe overdose complications.

Anonymous Patient Answer

What is opioid abuse?

A minority of patients were diagnosed with opioid use disorder. Opioid use disorder is a serious problem in the US. This disorder is marked by frequent opioid use, a history of heroin or opiate use, a poor response to addiction treatments, and psychiatric comorbidities and should be monitored very closely in drug-free populations.

Anonymous Patient Answer

Have there been any new discoveries for treating opioid abuse?

In the past ten years new medicines for treating opioid abuse in people with prescription drug issues have been introduced, and there has been a new medication for treating addiction. However, the benefits of these medications have not been shown in clinical studies. There are three key factors that all treatment for treating opioids: timing, effectiveness, and tolerability. You can search by clinical trial for the drugs you are looking for based on patient and trial characteristics. Your doctor may also recommend medication for opioid abuse or addiction.

Anonymous Patient Answer

Has case management and peer recovery proven to be more effective than a placebo?

Case management and peer recovery appear to be more effective than a placebo in the behavioral and medical treatment of drug dependence. The implications of this randomized, double-blind, clinical trial include the clinical ramifications and recommendations for future research into treatment of opiate dependence.

Anonymous Patient Answer

What are the latest developments in case management and peer recovery for therapeutic use?

Given the wide variety of services available for those with severe substance dependence, there must be a range of strategies and case management strategies for each. A multidisciplinary approach is often used to effectively resolve problems of social and psychiatric functioning through a number of programs, such as group treatment (e.g., community reinforcement approach, contingency management, cognitive behavioural, and dialectical behavior therapy) and individual therapy (e.g. methadone maintenance, contingency management, dialectical behavior therapy, CBT).

Anonymous Patient Answer

What is the average age someone gets opioid abuse?

It is important for health care providers to identify adolescents who are at high risk for opioid misuse. Results from a recent paper highlights the importance of expanding opioid education programs to include information about a number of drug issues that may be related to opioid misuse, such as alcohol, cannabis, prescription drugs, and street drugs. Programs should also educate adolescents on a variety of strategies for coping with the emotions that might drive opioid use.

Anonymous Patient Answer

How serious can opioid abuse be?

In the hospital setting, the serious but reversible health effects of opioid abuse may be as well known as its severe long-term consequences. These include chronic morphine toxicity, which has high mortality, as well as serious long-term toxicity that in an otherwise healthy young person can produce respiratory depression, bradycardia, and even death. The use of heroin is a particularly dangerous and life-threatening route of opioid abuse. Hospitals should be aware of the serious risks of opioid abuse and work with patients to find alternative treatments. To monitor and control opioid abuse and the consequences of abuse, it is best to set up a system similar to urine drug screens and medical prescription control or control of dispensing prescription drugs.

Anonymous Patient Answer

Have there been other clinical trials involving case management and peer recovery?

Despite the existence of case management trials in the past ten years, there is a need for more studies to provide more evidence on peer recovery for people with alcohol- and other substance use problems.

Anonymous Patient Answer
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