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Triamcinolone Acetonide 40mg/mL for Complex Regional Pain Syndrome

Phase 4
Waitlist Available
Led By Mark Campbell, MD
Research Sponsored by Ottawa Hospital Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up week 12
Awards & highlights

Study Summary

This trial will test the feasibility of performing a placebo-controlled RCT to study the efficacy and safety of peripheral nerve blocks in reducing pain for patients with CRPS.

Eligible Conditions
  • Complex Regional Pain Syndrome (CRPS)

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~week 12
This trial's timeline: 3 weeks for screening, Varies for treatment, and week 12 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Blinding - Interventionist
Blinding - Participant
Blinding - Physiotherapist
+5 more
Secondary outcome measures
Disease Severity - Complex Regional Pain Syndrome Severity Score
Emotional and Psychological Function - EQ-5D-5L
Emotional and Psychological Function - Patient-Reported Outcomes Measurement Information System 29 Profile V2
+7 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: TreatmentExperimental Treatment1 Intervention
The intervention group will receive: Suprascapular nerve block - 3 mL of 0.5% Bupivacaine and 1 mL of 40 mg/mL Kenalog Median nerve block - 3.5 mL of 0.5% Bupivacaine and 0.5 mL of 40 mg/mL Kenalog Ulnar nerve block - 3.5 mL of 0.5% Bupivacaine and 0.5 mL of 40 mg/mL Kenalog
Group II: PlaceboPlacebo Group1 Intervention
Placebo The placebo group will receive: Suprascapular nerve injection - 4 mL of normal saline Median nerve injection - 4 mL of normal saline Ulnar nerve injection - 4 mL of normal saline
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Triamcinolone
FDA approved

Find a Location

Who is running the clinical trial?

Ottawa Hospital Research InstituteLead Sponsor
561 Previous Clinical Trials
2,785,644 Total Patients Enrolled
Mark Campbell, MDPrincipal InvestigatorElisabeth Bruyere Hospital and The Ottawa Hospital

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What conditions is Triamcinolone Acetonide 40mg/mL considered an effective remedy for?

"Triamcinolone Acetonide 40mg/mL is traditionally used to treat ulcerative colitis but may also be beneficial for individuals with hand, brain, and dermatologic disorders."

Answered by AI

What are the objectives of this medical experiment?

"This 12-week clinical trial will be observed with the specific aim of blinding the physiotherapist. Secondary objectives include assessing emotional and psychological function using Patient-Reported Outcomes Measurement Information System 29 Profile V2, EQ-5D-5L, and Total Score - EQ-5D-5L as holistic indicators of efficacy. These measurements range from 16 to 80 (higher scores indicate worse outcomes) for PROMIS29V2, 1 to 5 (higher scores denote poorer results) in EQ-5D-5L, and 5 to 25 (worse performance is indicated by higher numbers)."

Answered by AI

Is the 40mg/mL concentration of Triamcinolone Acetonide certified by the FDA?

"Safety data gathered by our team at Power suggests that Triamcinolone Acetonide 40mg/mL is quite secure, rated a 3 on the 1-3 scale. This medication has recently been approved as part of Phase 4 trials."

Answered by AI

Is there a limit to how many people are eligible for this medical experiment?

"This clinical trial is no longer looking for participants. It was published on March 1st 2021 and the listing most recently updated on February 3rd 2021. If you are seeking other studies, currently there 1393 trials recruiting patients with complex regional pain syndromes, as well as 41 medical experiments involving Triamcinolone Acetonide 40mg/mL that are actively enrolling subjects."

Answered by AI

Are there any vacancies left for prospective volunteers in this experiment?

"As indicated on clinicaltrials.gov, this medical trial has ceased to recruit participants as of February 3rd 2021; however, there are 1,434 other studies actively enrolling patients at the moment."

Answered by AI

Are there any precedents for this type of clinical trial utilizing Triamcinolone Acetonide 40mg/mL?

"Presently, 41 experiments are underway that investigate Triamcinolone Acetonide 40mg/mL. 8 of those studies have progressed to the third stage, and 75 different sites distribute this medication all over Columbia, Missouri."

Answered by AI
~12 spots leftby Apr 2025