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Behavioural Intervention

Patients Receiving rTMS for Smoking

Phase 4

Recruiting

Led By Victor Tang, MD, MSc

Research Sponsored by Centre for Addiction and Mental Health

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through study completion, an average of 1 year

Awards & highlights

Study Summary

This trial aims to see if using repetitive transcranial magnetic stimulation (rTMS) can help people quit smoking. rTMS uses a magnetic field to stimulate specific areas of the brain involved in

Who is the study for?

This trial is for daily smokers who want to quit and are willing to attend treatment sessions at the Center for Addiction and Mental Health in Toronto. Participants must complete surveys and interviews, undergo 3 weeks of daily rTMS treatments followed by weekly sessions for another 3 weeks.Check my eligibility

What is being tested?

The study tests repetitive transcranial magnetic stimulation (rTMS) using Brainsway H4 deep rTMS coil and stimulator system on two brain regions linked to addiction cravings and decision-making. The aim is to assess if this non-invasive method can help smokers quit by stimulating these areas.See study design

What are the potential side effects?

Potential side effects of rTMS may include discomfort at the stimulation site, headache, lightheadedness, or seizures in very rare cases. Most people tolerate it well with minimal discomfort.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through study completion, an average of 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through study completion, an average of 1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an average of 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Identify contextual determinants of rTMS adoption and reach NDC through a qualitative approach.

Identify rates of adoption of rTMS in Nicotine Dependence Clinic

The primary objective of the study is to evaluate the feasibility of implementing rTMS in the Nicotine Dependence Clinic (NDC) at CAMH, in Toronto. This is determine by reach, the extent to which patients are engaging in the rTMS treatment.

Secondary outcome measures

Evaluate the effectiveness of rTMS on smoking cessation rates in real world patients with common comorbidities seeking treatment at NDC.

Explore patient-HCP communication about shared treatment decision-making for rTMS.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Patients Receiving rTMSExperimental Treatment1 Intervention

Participants will receive 3 weeks of daily (Monday to Friday) rTMS sessions followed by 3 weeks of weekly rTMS sessions for a total of 6 weeks of treatment. Each session lasts about 25 minutes and is provided by an rTMS technician at the Temerty Center at 1025 Queen Street West, with medical supervision.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Centre for Addiction and Mental HealthLead Sponsor

356 Previous Clinical Trials

81,418 Total Patients Enrolled

6 Trials studying Smoking

9,817 Patients Enrolled for Smoking

Victor Tang, MD, MScPrincipal InvestigatorCenter for Addiction and Mental Health

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does the FDA endorse the utilization of rTMS for patients?

"Our evaluation at Power rates the safety of patients undergoing rTMS with a score of 3. This is due to the Phase 4 nature of the trial, signifying that this treatment has already been sanctioned for use."

Answered by AI

Is the clinical trial open to individuals younger than 60 years old?

"For potential participation in this research study, individuals must be at least 18 years old but no more than 70 years of age."

Answered by AI

What is the total number of participants being recruited for this research investigation?

"Indeed, information from clinicaltrials.gov indicates that this medical trial is actively seeking volunteers. The trial was first listed on March 30th, 2024 and underwent its most recent update on March 28th, 2024. The research aims to recruit a total of 40 participants from one designated site."

Answered by AI

Are participants currently being actively enrolled in this trial?

"As per clinicaltrials.gov, this current medical trial is actively seeking participants. The trial was initially uploaded on 3/30/2024 and last revised on 3/28/2024."

Answered by AI

Recent research and studies

AddictionJournal

Effects of Repetitive Transcranial Magnetic Stimulation (rtms) on Craving and Substance Consumption in Patients with Substance Dependence: A Systematic Review and Meta‐analysis

Zhang, Jack J. Q., Kenneth N. K. Fong, Rang‐ge Ouyang, Andrew M. H. Siu, and Georg S. Kranz. 2019. “Effects of Repetitive Transcranial Magnetic Stimulation (rtms) on Craving and Substance Consumption in Patients with Substance Dependence: A Systematic Review and Meta‐analysis”. Addiction. Wiley. doi:10.1111/add.14753.

clinicaltrials.govStudy

Implementation of Transcranial Magnetic Stimulation for Smoking Cessation

2024. "Implementation of Transcranial Magnetic Stimulation for Smoking Cessation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06346028.

All > Transcranial Magnetic Stimulation > Smoking Cessation