Hiv Infection Clinical Trials 2022

Browse 165 Hiv Infection Medical Studies Across 151 Cities

20 Phase 3 Trial · 922 Hiv Infection Clinics

Reviewed by Michael Gill, B. Sc.
Phase-Based Progress Estimates

PrEPfor HIV Infections

Toronto, Canada
Any Age
Gay, bisexual and other men who have sex with men (GBM) account for over half of new HIV infections in Canada each year, and have a 131-fold higher risk of HIV than other Canadian men. HIV pre-exposure prophylaxis (PrEP) using regular oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) or tenofovir alafenamide/emtricitabine (TAF/FTC) is an effective and safe HIV prevention option. Despite growing interest, awareness and willingness to use PrEP there has been numerous challenges to the broader rollout of PrEP. This study will address some of these challenges by assessing participant satisfaction,feasibility and clinical outcomes associated with a web-based mobile health (mHealth) model of care for daily oral TAF/FTC PrEP compared to standard of care delivery of TAF/FTC PrEP in Canadian GBM/TGW, in the era of COVID-19. The ultimate goal of this study is to provide a scalable model for remote PrEP delivery that minimizes the need for in-person interactions; respects guideline recommendations regarding how to optimally monitor patients; and is attractive to both patients and providers. This study is a 1:1 open-label, pragmatic randomized controlled trial using a AB:BA crossover design, comparing the standard of care to an mHealth based model of care (Freddie® ) for TAF/FTC PrEP delivery over 72 weeks.
Phase 4
Waitlist Available
25 Hiv Infection Clinical Trials Near Me
Saint Louis, MO
Seattle, WA
Philadelphia, PA
Cincinnati, OH
More Trial Locations
An interactive map to display trial locations for Washington University Therapeutics (WT) CRS, University of Washington AIDS CRS, Penn Therapeutics CRS, Cincinnati Children's Hosp / Univ Hosp, and 78 more locations.
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Tenofovir Disoproxil Fumarate
Tenofovir disoproxil + Emtricitabine
Eastern Virginia Medical School
Relapse Prevention Text Messaging
VA Office of Research and Development

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 28th, 2021

Last Reviewed: August 30th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.