SIRI Checklist for Pre-Exposure Prophylaxis

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Alabama at Birmingham, Birmingham, AL
Pre-Exposure Prophylaxis+2 More
SIRI Checklist - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

The purpose of this study is to develop and test a serious injection-related injections (SIRI) checklist aimed at increasing evidence-based treatment for rural people who use drugs (PWUD) including innovative, long-acting injectable agents. The central hypothesis is that hospital-based care models can successfully engage rural and Southern (PWUD) in effective addiction treatment and infection prevention. The activities in this study will be foundational to Ending the HIV epidemic in rural states.

Eligible Conditions

  • Pre-Exposure Prophylaxis
  • HIV Infections
  • Opioid Abuse

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 3 Secondary · Reporting Duration: Enrollment until 3 months post-enrollment.

Month 3
Number of outpatient visit(s)attended related to HIV and/or addiction services following hospitalization.
Number of prescription for medications for opioid use disorder (MOUD)
Number of prescriptions for PrEP (pre-exposure prophylaxis)
Month 3
Acceptability Assessment
Month 3
Feasibility Assessment

Trial Safety

Safety Progress

1 of 3

Trial Design

4 Treatment Groups

Standard of Care
1 of 4
SIRI Checklist + Enhanced Peer Recovery Coach
1 of 4
SIRI Checklist
1 of 4
Enhanced Peer Recovery Coach
1 of 4
Active Control
Experimental Treatment

60 Total Participants · 4 Treatment Groups

Primary Treatment: SIRI Checklist · No Placebo Group · N/A

SIRI Checklist + Enhanced Peer Recovery Coach
Behavioral
Experimental Group · 1 Intervention: SIRI Checklist + Enhanced Peer Recovery Coach · Intervention Types: Behavioral
SIRI Checklist
Behavioral
Experimental Group · 1 Intervention: SIRI Checklist · Intervention Types: Behavioral
Enhanced Peer Recovery Coach
Behavioral
Experimental Group · 1 Intervention: Enhanced Peer Recovery Coach · Intervention Types: Behavioral
Standard of CareNoIntervention Group · 1 Intervention: Standard of Care · Intervention Types:

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: enrollment until 3 months post-enrollment.
Closest Location: University of Alabama at Birmingham · Birmingham, AL
Photo of university of alabama at birmingham 1Photo of university of alabama at birmingham 2Photo of university of alabama at birmingham 3
1991First Recorded Clinical Trial
0 TrialsResearching Pre-Exposure Prophylaxis
1070 CompletedClinical Trials

Who is running the clinical trial?

University of Alabama at BirminghamLead Sponsor
1,402 Previous Clinical Trials
2,211,003 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 1 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.