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Behavioral Intervention

TXTXT Intervention for HIV Adherence

N/A

Recruiting

Led By Amy Johnson, PhD

Research Sponsored by Ann & Robert H Lurie Children's Hospital of Chicago

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 12 months

Awards & highlights

Study Summary

This trial will evaluate if TXTXT intervention can help improve adherence & viral load suppression in young people living with HIV.

Who is the study for?

This trial is for young people aged 16-35 with HIV who are on antiretroviral therapy (ART) but have a viral load of ≥200c/mL or haven't been taking their medication regularly. They must be able to get text messages and give informed consent, and they should already be patients at one of the participating clinics.Check my eligibility

What is being tested?

The study compares two groups in different clinics: one gets standard HIV care, while the other receives an additional text message-based intervention called TXTXT aimed at improving medication adherence. The effectiveness will be measured by how well participants stick to their ART regimen and their viral load after 3 and 6 months.See study design

What are the potential side effects?

Since this trial involves a non-medical intervention (text messaging), there are no direct medical side effects associated with it. However, participants may experience issues related to privacy if personal information is shared via texts.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

HIV Medication Adherence

HIV-1 RNA Viral Load

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: InterventionExperimental Treatment1 Intervention

Clinics randomized to the intervention arm will have participants complete a 6-month intervention period. Clinics will sign up eligible participants to receive automated SMS messages from the Dimagi CommCare platform during the participant's baseline study visit. Participants will have the option to tailor the message content based on their own preferences and will be able to select to receive messages in English or in Spanish, the time the messages are delivered, and frequency of messages. Clinic staff will enter this information in the Dimagi CommCare platform, and then test receipt of text messages by the participant before they complete this baseline visit.

Group II: ComparisonActive Control1 Intervention

Clinics randomized to the comparison arm will have participants receive standard of care ART adherence support for 3 months, and will receive the TXTXT intervention for 3 months. The standard of care for ART adherence across clinic sites consists of routine follow-up from assigned case managers for appointment reminders and adherence counseling at scheduled visits .

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Howard Brown Health CenterOTHER

10 Previous Clinical Trials

7,612 Total Patients Enrolled

KC Care Health CenterUNKNOWN

1 Previous Clinical Trials

200 Total Patients Enrolled

Ann & Robert H Lurie Children's Hospital of ChicagoLead Sponsor

258 Previous Clinical Trials

5,188,530 Total Patients Enrolled

Media Library

Standard of Care (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05783297 — N/A

Human Immunodeficiency Virus Infection Research Study Groups: Intervention, Comparison

Human Immunodeficiency Virus Infection Clinical Trial 2023: Standard of Care Highlights & Side Effects. Trial Name: NCT05783297 — N/A

Standard of Care (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05783297 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Could you inform me of the various venues in which this research is being conducted within the state?

"In addition to Howard Brown Health in Chicago, IL and Eskenazi Health in Indianapolis, IN, this trial is also occurring out of Indiana University in Lake Charles, LA. There are 11 other sites that have been approved for study participation."

Answered by AI

Does this clinical trial stipulate a minimum age requirement?

"To be considered for this medical trial, patients must be aged between 16 and 35. Conversely, there are 109 studies recruiting individuals younger than that age bracket and 340 trials targeting seniors 65 years old or older."

Answered by AI

How many participants are being admitted into this experiment?

"This clinical trial calls for 600 participants with the required qualifications. Patients can be enlisted from several locations, including Howard Brown Health in Chicago and Eskenazi Health near Indianapolis."

Answered by AI

Are there openings available to join this research project now?

"Affirmative. Clinicaltrials.gov data demonstrates that this clinical trial, which was initially announced April 17th 2023, is actively searching for participants. 600 individuals need to be enrolled from 11 different medical centres."

Answered by AI

Could I qualify to participate in this trial?

"This clinical study is recruiting 600 individuals that meet the following criteria: Infected with HIV, aged between 16-35 years old, currently medicated and able to report a viral load of ≥200c/mL or demonstrate poor adherence (<90% of pills taken in the last 30 days), capable of receiving text messages, and willing to participate after providing informed consent."

Answered by AI

Recent research and studies

Implementation ScienceJournal

Fostering Implementation of Health Services Research Findings into Practice: A Consolidated Framework for Advancing Implementation Science

Damschroder, Laura J, David C Aron, Rosalind E Keith, Susan R Kirsh, Jeffery A Alexander, and Julie C Lowery. 2009. “Fostering Implementation of Health Services Research Findings into Practice: A Consolidated Framework for Advancing Implementation Science”. Implementation Science. Springer Science and Business Media LLC. doi:10.1186/1748-5908-4-50.

clinicaltrials.govStudy

Midwest TXTXT Scale up of an Evidence-Based Intervention to Promote HIV Medication Adherence

2023. "Midwest TXTXT Scale up of an Evidence-Based Intervention to Promote HIV Medication Adherence". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05783297.