Study Summary
This trial is testing a new way to treat back pain that is caused by arthritis in the facet joints.
- Lumbar Facet Osteoarthritis
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 3 Secondary · Reporting Duration: 6, 12, 26, 52 weeks
Trial Safety
Trial Design
2 Treatment Groups
Corticosteroid injection
1 of 2
Adipose-derived stem cell injection
1 of 2
Active Control
Experimental Treatment
40 Total Participants · 2 Treatment Groups
Primary Treatment: Adipose-derived stem cell injection · No Placebo Group · N/A
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18 - 75 · All Participants · 10 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| Florida | 100.0% |
What site did they apply to?
| Sports and Orthopedic Center | 100.0% |
What portion of applicants met pre-screening criteria?
| Met criteria | 100.0% |
- Toghraie, F.S., N. Chenari, M.A. Gholipour, Z. Faghih, S. Torabinejad, S. Dehghani, and A. Ghaderi. 2011. “Treatment of Osteoarthritis with Infrapatellar Fat Pad Derived Mesenchymal Stem Cells in Rabbit”. The Knee. Elsevier BV. doi:10.1016/j.knee.2010.03.001.
- ter Huurne, Menno, Rik Schelbergen, Roxane Blattes, Arjen Blom, Wouter de Munter, Lilyanne C. Grevers, Jannik Jeanson, et al.. 2012. “Antiinflammatory and Chondroprotective Effects of Intraarticular Injection of Adipose-derived Stem Cells in Experimental Osteoarthritis”. Arthritis & Rheumatism. Wiley. doi:10.1002/art.34626.
- ter Huurne M, Schelbergen R, Blattes R, Blom A, de Munter W, Grevers LC, Jeanson J, Noel D, Casteilla L, Jorgensen C, van den Berg W, van Lent PL. Antiinflammatory and chondroprotective effects of intraarticular injection of adipose-derived stem cells in experimental osteoarthritis. Arthritis Rheum. 2012 Nov;64(11):3604-13. doi: 10.1002/art.34626.
- 2018. "Safety of Adipose-derived Regenerative Cells Injection for Treatment of Osteoarthritis of the Facet Joint". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03513731.
Frequently Asked Questions
Is enrollment for this trial ongoing?
"According to clinicaltrials.gov, this trial is still enlisting participants as of May 16th 2022. It was initially published on December 7th 2018 and has been updated since then." - Anonymous Online Contributor
Could I join the research project?
"This trial is looking for 40 individuals between 18 and 75 years old who are suffering from arthrosis. Essential requirements include: both male and female participants, a minimum of 6 months of chronic low [back pain](https://www.withpower.com/clinical-trials/back-pain) treatment with conservative measures such as medications or physical therapy, radiographic evidence of an alteration in spinal morphology at the symptom level, a baseline pain score on a 0-10 scale that exceeds 4 over 24 hours., relief after diagnostic injection exceeding 80%, willingness to participate willingly throughout the study period indicated by signed informed consent." - Anonymous Online Contributor
To what extent is enrollment in this clinical trial progressing?
"Absolutely, according to clinicaltrials.gov this research trial is actively recruiting patients as of May 16th 2022. The study was initially posted on December 7th 2018 and seeks 40 participants from 1 medical site." - Anonymous Online Contributor
Does this research initiative embrace subjects aged 35 and up?
"The ages of participants admitted into this clinical trial range from 18 to 75. Additionally, there are 30 trials for minors and 583 trials open to seniors." - Anonymous Online Contributor