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Carotenoids

Pistachio Group for Macular Degeneration

N/A
Recruiting
Led By Tammy Scott
Research Sponsored by Tufts University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up measured at baseline, 6 weeks and 12 weeks.
Awards & highlights

Summary

This trial tests if eating pistachios can help older adults by protecting their eyes from light damage and improving brain function. Pistachios contain nutrients that are beneficial for eye and brain health. Pistachios contain protein, carbohydrate, dietary fibers, fat, folic acid, vitamin K, magnesium and potassium, gama-tocopherols, phytochemicals, and polyphenols, which have antioxidant and anti-inflammatory functions.

Eligible Conditions
  • Age-Related Macular Degeneration
  • Retinal Degeneration
  • Retinal Disease
  • Eye Diseases

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~measured at baseline, 6 weeks and 12 weeks.
This trial's timeline: 3 weeks for screening, Varies for treatment, and measured at baseline, 6 weeks and 12 weeks. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change from baseline Macular Pigment (MP) Density over 12 weeks
Secondary study objectives
Serum concentrations of lutein and zeaxanthin (dietary carotenoids)

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Pistachio GroupExperimental Treatment1 Intervention
The pistachio group will receive pistachio nuts in 2-ounce packs. This group will consume one pack every day over the course of the 12-week study.
Group II: Control (Usual Diet) GroupActive Control1 Intervention
The control group will not receive pistachio nuts. They will be asked to make no changes and continue to eat their regular diet.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Pistachio Group
2017
N/A
~120

Find a Location

Who is running the clinical trial?

Tufts UniversityLead Sponsor
270 Previous Clinical Trials
598,543 Total Patients Enrolled
American Pistachio GrowersOTHER
4 Previous Clinical Trials
230 Total Patients Enrolled
Tammy ScottPrincipal InvestigatorTufts University

Media Library

Pistachio Group (Carotenoids) Clinical Trial Eligibility Overview. Trial Name: NCT05283941 — N/A
Age-Related Macular Degeneration Research Study Groups: Pistachio Group, Control (Usual Diet) Group
Age-Related Macular Degeneration Clinical Trial 2023: Pistachio Group Highlights & Side Effects. Trial Name: NCT05283941 — N/A
Pistachio Group (Carotenoids) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05283941 — N/A
~12 spots leftby Oct 2025