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Neuromodulation

Neuromodulation for Pain Management

N/A
Recruiting
Research Sponsored by Virginia Polytechnic Institute and State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up participant study duration, approximately 3 weeks.
Awards & highlights

Study Summary

This trial is looking at whether a noninvasive brain stimulation technique can change brain signals in a way that may help people with addiction, pain, or mental health conditions.

Who is the study for?
This trial is for healthy volunteers from any ethnic background who can understand and speak English. It's not suitable for pregnant individuals, those with certain metal implants, a history of significant head injury, claustrophobia, neurological disorders like Parkinson's or epilepsy, active central nervous system conditions such as Alzheimer's, or a history of substance dependence.Check my eligibility
What is being tested?
The study tests how low-intensity focused ultrasound (LIFU) affects brain activity related to pain. Participants undergo MRI and CT scans along with LIFU treatment. Changes in brain signals are monitored through fMRI after LIFU while experiencing controlled heat sensations. The study spans over four visits including questionnaires and vital signs monitoring.See study design
What are the potential side effects?
While the document doesn't specify side effects directly associated with LIFU in this context, typical concerns may include discomfort during imaging procedures or potential transient changes in brain function due to neuromodulation.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~participant study duration, approximately 3 weeks.
This trial's timeline: 3 weeks for screening, Varies for treatment, and participant study duration, approximately 3 weeks. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
fMRI BOLD Signals
Secondary outcome measures
Changes in self-reported perceived pain
Other outcome measures
Monitoring changes to physiological measures

Trial Design

1Treatment groups
Experimental Treatment
Group I: LIFU, heat evoked fMRI signalsExperimental Treatment1 Intervention
fMRI resting and heat evoked signals performed after LIFU application to known brain region of interest or active sham region (within participant all conditions tested).

Find a Location

Who is running the clinical trial?

Virginia Polytechnic Institute and State UniversityLead Sponsor
139 Previous Clinical Trials
27,544 Total Patients Enrolled
1 Trials studying Pain
116 Patients Enrolled for Pain

Media Library

Low-intensity Focused Ultrasound (Neuromodulation) Clinical Trial Eligibility Overview. Trial Name: NCT05303415 — N/A
Pain Research Study Groups: LIFU, heat evoked fMRI signals
Pain Clinical Trial 2023: Low-intensity Focused Ultrasound Highlights & Side Effects. Trial Name: NCT05303415 — N/A
Low-intensity Focused Ultrasound (Neuromodulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05303415 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Am I eligible to participate in this study?

"Candidates eligible for this clinical research must have chronic pain and be between 18-65 years of age. This study is accepting a maximum of 80 participants."

Answered by AI

How many participants can partake in this medical experiment?

"Affirmative. According to the clinicaltrials.gov website, this test is currently open for enrollment and was posted on May 6th 2022 before its most recent update on July 27th 2022. 80 persons are required from a single medical centre to join the trial."

Answered by AI

Does the age criterion for this medical research extend beyond 80 years?

"This clinical trial requires participants to fall within the age range of 18-65. For those outside this demographic, there are 71 additional studies for individuals younger than eighteen and 248 more suited for persons above sixty-five years old."

Answered by AI

Are there still vacancies for volunteers in this research endeavor?

"According to the records on clinicaltrials.gov, this research endeavour is still accepting patients. The trial was initially published on May 6th 2022 and underwent its most recent update at the end of July that same year."

Answered by AI
~3 spots leftby May 2024