Cordotomy for Cancer

Locally Advanced
Recruiting · 18+ · All Sexes · Houston, TX

This study is evaluating whether a surgery which reduces pain in cancer patients is effective.

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About the trial for Cancer

Eligible Conditions
Neoplasms · Advanced Malignant Neoplasm

Treatment Groups

This trial involves 2 different treatments. Cordotomy is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are not being studied for commercial purposes.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
Questionnaire Administration
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.
Sham Intervention
Questionnaire Administration

About The Treatment

First Studied
Drug Approval Stage
How many patients have taken this drug


This trial is for patients born any sex aged 18 and older. There are 4 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Pain that is equal to or greater than 4 on a 0 to 10 numerical scale. show original
Ability to provide informed consent
The text has undergone three evaluations to provide palliative care. show original
Unilateral pain due to cancer below the shoulder level (arm, trunk, hip, leg)
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Odds of Eligibility
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial

Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: Up to 6 months
Screening: ~3 weeks
Treatment: Varies
Reporting: Up to 6 months
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: Up to 6 months.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Cordotomy will improve 1 primary outcome and 2 secondary outcomes in patients with Cancer. Measurement will happen over the course of Up to 6 months.

Other ESAS symptoms
Will provide initial estimates of the magnitude of the effect of cordotomy.
Brief Pain Inventory pain interference items
Will provide initial estimates of the magnitude of the effect of cordotomy.
Reduction in pain intensity
Will be measured by the Edmonton Symptom Assessment Scale (ESAS).

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the signs of cancer?

Signs of cancer in children and adolescents include an unexplained weight loss, painful or difficult walking, bleeding in the nose, coughing or hoarseness, swollen lymph nodes, and poor wound healing. Children with a family history of breast cancer or skin cancer are at higher risk as are girls who have had a child with a particular type of cancer.

Anonymous Patient Answer

What is cancer?

It is extremely important for medical students to acquire sufficient knowledge about cancer so that they can recognize, discuss and provide appropriate treatment in a timely and appropriate manner when a diagnosis is made.

Anonymous Patient Answer

What are common treatments for cancer?

The current study supports that treatments of cancer are variable and that they are largely unplanned. There are some common types of medication used, but there is no clear agreement as to what medications should be used or when medication should be used. The present survey of treatment options suggests that, more generally, there is no agreement among doctors about which treatments to use for a particular problem. This survey shows that there is no clear agreement on which treatments are most reasonable for cancer, and this is not likely to change. Data from a recent study reinforces the importance of a collaborative approach between treating doctors, doctors' professional bodies (e.g.

Anonymous Patient Answer

Can cancer be cured?

The present findings show that when patients with cancer are followed through a series of surgeries, chemotherapy and radiation, cancer can be cured. There are still many questions about whether cancer can be wholly eliminated, but the data show that cancer is not a fatal disease, and that its cure can be had, if it is detected as quickly as can be.

Anonymous Patient Answer

What causes cancer?

Although many different factors can cause cancer, it is the accumulation of mutations in tumor cells that cause this deadly disease. Oncogenes are special genes that drive cell growth, and tumor suppressor genes manage cell growth. The body’s immune system, particularly the adaptive immune system, can be a powerful tool for fighting off cancer. The adaptive immune system is made up of white blood cells that work to recognize and kill cancer cells. Other factors can contribute to the genesis and development of cancer, but it is the accumulation of mutations that will cause tumor formation or spread. http://mcr.

Anonymous Patient Answer

How many people get cancer a year in the United States?

Almost 100,000 patients are diagnosed with cancer each year in the USA. Lung cancer is the second leading cause of cancer death in men, and colon cancer is the second leading cause of cancer death in women.

Anonymous Patient Answer

What are the latest developments in cordotomy for therapeutic use?

New approaches to cordotomy including newer types of electrodes, cordotomy coils, electrodes that can be used for an extended time period, cordotomy coils that have the ability to be placed on either end of the cord without crushing the cord, and a new technique for cutting that avoids cricothyrotomy.

Anonymous Patient Answer

Does cancer run in families?

The risk of developing cancer in this study was not found to be significantly different between siblings with and without family history. No risk factors were detected. Thus, there is no evidence that cancer seems to run in families. If cancer does run in families we need to understand how and where there are those families at higher risk for certain types of cancer. Therefore, we must identify and understand those genetic predisposition for cancer.

Anonymous Patient Answer

Have there been other clinical trials involving cordotomy?

No randomized controlled trials of Cordotomy have ever been reported and so the evidence base is limited. A careful appraisal of the evidence indicates that Cordotomy is an unlikely procedure for any clinical condition, including cancer. However, it has been offered to some patients with non-muscle invasive bladder cancer although evidence on cordotomy is limited. When patients are offered the option of undergoing cordotomy, their likelihood to choose it and their attitudes towards cordotomy are monitored. If it is accepted, cordotomy is likely to be poorly tolerated and it is not currently considered appropriate treatment for cancer.

Anonymous Patient Answer

What is the average age someone gets cancer?

The lifetime risk of developing cancer appears to be about 1 in 50 for males and 1 in 71 for females, with both sexes being equally likely to develop the disease.

Anonymous Patient Answer

What is the primary cause of cancer?

The genetic causes of cancer are complex and vary with cancers and cells of that specific cell type.  For cancer cells, the cellular replication rate and the amount of DNA damage can cause alterations in the genome as well as a loss or gain of chromosomal integrity.\n\nWhen a cell divides, it is required for a new set of cells to be created to fill up the body. The process of cell reproduction requires a high concentration of nutrients available for the cell to duplicate, which are commonly produced from proteins and nucleic acids. The nuclei of these cell are capable of dividing twice in a day and are therefore quite sensitive to nutrients or toxins in the environment.

Anonymous Patient Answer

Has cordotomy proven to be more effective than a placebo?

Cordotomy is much more effective than a control group in controlling spasm of the pelvic floor. The efficacy of an experimental regimen is limited by the degree of compliance with the treatment.

Anonymous Patient Answer
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