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Cannabis for Cancer-Related Symptoms (CAFCARS Trial)
CAFCARS Trial Summary
This trial will test the effectiveness of three cannabis oil extract combinations (High THC-Low CBD, Low THC-High CBD, or Equal amounts of THC and CBD) in a minimum of 120 cancer patients on 4 cancer-related symptoms: nausea, pain, anxiety and sleep disturbance.
CAFCARS Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowCAFCARS Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.CAFCARS Trial Design
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Who is running the clinical trial?
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- I can be reached by phone.I cannot or will not avoid using heavy machinery during the study.I am 19 years old or older.I am mentally capable of understanding and agreeing to participate in the study.You live in a place where there's a high chance that the study medication could be stolen or used improperly.I experience significant nausea, pain, anxiety, or sleep issues due to my cancer or its treatment.I experience significant nausea, pain, anxiety, or sleep problems due to my cancer or its treatment.You have used cannabis more than once a week in the month before the study.You have had mental health issues related to cannabis or cannabinoids.I have a history of epilepsy, seizures, or brain cancer spread.I am on medication that can't mix with cannabinoids and can't be changed.I can communicate effectively with the research team, with or without a translator.I need to change my current medications due to another health condition while on the study treatment.I am a woman who can still have children and am not using certain birth control methods.My current symptoms are not caused by my cancer or its treatment.My symptoms are expected to remain the same during the study.You currently have a problem with using cannabis or other substances, as determined by a specific test score.You are expected to live for at least 4 months.I have mouth conditions that could affect medicine absorption.I can take care of myself and am up and about more than half of my waking hours.I do not have serious heart problems like recent heart attacks or uncontrolled high blood pressure.I have a parent or sibling with schizophrenia.
- Group 1: High THC/Low CBD Cannabis Oil
- Group 2: Low THC/High CBD Cannabis Oil
- Group 3: Equal amounts of THC/CBD Cannabis Oil
- Group 4: Placebo Oil
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Could you please share any other studies that have been done on Cannabis?
"Currently, 73 studies on Cannabis are ongoing with 9 of them in the critical third phase. Most of these trials are taking place in Belmont, Massachusetts; however, 159 centres across the globe are running clinical trials for Cannabis."
Are there risks associated with using Cannabis?
"There is some clinical data surrounding cannabis that supports its safety, but since this is only a Phase 2 trial, efficacy has not been proven."
For what conditions is Cannabis most often recommended as a treatment?
"Cannabis is frequently leveraged by patients to manage weight loss. Other potential benefits include its ability to help those who haven't responded well to traditional treatments, as well as reducing appetite loss."
Are we still recruiting participants for this research project?
"Yes, this is an ongoing clinical trial that is still recruiting patients. The original posting was on February 1st, 2021 with the most recent edit being on August 10th, 2022."
How many people are enrolled in this clinical trial at the most?
"The clinical trial is actively recruiting participants, according to the listing on clinicaltrials.gov. The trial was posted on February 1st, 2021 and last updated on August 10th, 2022. They are looking for 150 people to participate at a single location."
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