Popular Trials
Ovarian Reserve Testing for Infertility in Cancer Survivors
This trial is testing if two measures of ovarian reserve - blood draws and pelvic ultrasounds - can accurately predict if a young adult cancer survivor will experience a return of menses. The trial will also compare the results of the ovarian reserve measures between cancer survivors and healthy controls, and between cancer survivors taking and not taking combined estrogen and progesterone hormone products.
Behavioral Intervention
Patient Navigator Program for Infertility
This trial aims to study how a program called Patient Navigator (PN) can help underserved individuals at Boston Medical Center who are seeking infertility care. The main goal is to see if the PN program can
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Trials for Female Infertility Patients
Behavioral Intervention
Mindset Management for Stress in Women With Infertility
This trial aims to see if a mindset management program called Organic Conceptions can reduce stress levels in women with infertility. Participants will be divided into two groups, with one group receiving the program and the other
Behavioral Intervention
Fit-for-Fertility Program for Female Infertility and Obesity
This trial tests the Fit-For-Fertility program, which helps women with obesity and infertility adopt healthier lifestyles. The program includes sessions with dietitians and kinesiologists, and group education. It aims to improve fertility and reduce treatment costs by promoting sustainable healthy habits.
Procedure
Trigger Timing in Controlled Ovarian Stimulation for Female Infertility
This trial will compare the efficacy of two different times of administration of medications for final oocyte maturation, commonly called a "trigger", in cycles of controlled ovarian stimulation.
Hormone Therapy
Estradiol Patches for Female Infertility
"This trial will investigate whether obesity affects how the brain responds to hormones related to reproduction in women. The study will look at how obesity may lead to a decreased hormone response in the brain, potentially affecting the
Trials for Male Infertility Patients
Selective Serotonin Reuptake Inhibitor
Escitalopram for Sperm DNA Fragmentation
This trial is testing the effects of escitalopram, a common antidepressant, on healthy men with normal fertility and no history of mental health issues. Researchers want to see if this medication affects sperm quality and overall fertility. The results will help doctors advise men who are concerned about fertility and are taking or considering taking escitalopram.
Dietary Supplement
Power Prenatal Vitamins for Male Infertility
This trial focuses on male factor infertility, which is a common cause of infertility due to poor sperm quality. The study aims to test the effectiveness of a male fertility supplement called "Power Prenatal for
Device
Home Semen Testing for Male Infertility
This trial is looking to see if home semen testing is a feasible and useful way to screen for male factor infertility. They will also be looking at the impact that home semen testing has on fertility-related quality of life and whether or not it increases the diagnosis and treatment of male infertility.
Dietary Supplement
Prenatal Supplements for Male Infertility
This trial tests if a few months of taking the 'Power Prenatal for Sperm' supplement can improve sperm quality in men with infertility issues. The supplement contains nutrients that may help improve sperm concentration, movement, and shape.
Phase 3 Trials
GnRH Antagonist
Pre-IVF GnRH Antagonist for Endometriosis-related Infertility
This trial tests a pill that helps women with endometriosis who are undergoing IVF. These women often have lower success rates with IVF, and the pill helps manage hormone levels to improve their chances of having a baby.
Polyphenol
Fibroids & Infertility
This trial tests if a low caffeine green tea extract with high EGCG can help women aged 18-40 with fibroids get pregnant. The EGCG may shrink fibroids and improve the uterus lining, increasing pregnancy chances. EGCG, a major component of green tea, has been studied for its potential benefits in reducing uterine fibroids and improving reproductive health.
Trials With No Placebo
Procedure
Sperm Sorting for Gender Selection in Infertility Treatment
This trial is testing a method to choose sperm that will result in either a boy or a girl before fertilization. It targets couples undergoing infertility treatment. The process involves sorting sperm by density to identify male or female sperm, then using them for fertilization procedures like IVF or intrauterine insemination.
Genetic Testing
niPGT-A for Infertility
This trial tests a new, non-invasive method to check embryos for chromosomal issues by analyzing DNA in the culture medium. It aims to help IVF patients who prefer not to use invasive testing. The goal is to improve pregnancy rates by selecting the healthiest embryos without needing invasive procedures. This method emerged from the discovery of embryonic DNA in spent embryo culture medium.
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Frequently Asked Questions
Introduction to infertility
What are the top hospitals conducting infertility research?
Infertility can be a challenging and emotional journey for many couples, but there is hope in the form of clinical trials conducted by top hospitals around the world. In Regina, Canada, the University of Regina is making strides with four active infertility trials. Although they may have a smaller number of all-time trials (four), their commitment to researching and finding solutions for this condition is evident since recording their first trial in 2021.
Meanwhile, Boston IVF in Waltham has been at the forefront of infertility research since 1999 when they initiated their inaugural trial. With three ongoing infertility trials and an impressive history of 23 completed studies, this institution exemplifies dedication to understanding and addressing fertility challenges.
In New york City, Weill Cornell Medicine joins the ranks with three active infertility trials. Since conducting their first trial in 2012, they have made significant contributions to advancing our knowledge regarding fertility issues through six previously conducted investigations.
Further south in Clearwater, Florida's Women's Medical Research Group holds two current infertility trials while having accomplished six earlier studies dating back to their pioneering investigation on such cases starting from2008.Located outside Philadelphia, Main Line Fertility also plays a pivotal role with two ongoing clinical tests as well as contributing towards paving new paths through five previous investigations; theirs are traced back only seven years ago until2014.
These hospitals stand as beacons of hope for individuals struggling with infertility. Their relentless pursuit of knowledge and innovative treatment options brings us closer to fulfilling dreams of parenthood worldwide while reminding us that no obstacle is insurmountable when faced with passion-driven medical advancements
Which are the best cities for infertility clinical trials?
When it comes to infertility clinical trials, several cities stand out as hubs of research and innovation. In New york, there are currently 10 active trials focusing on treatments like sperm sorting, gamete treatment, and in vitro maturation. Chicago follows closely with 7 ongoing studies exploring the potential benefits of interventions such as green tea extract and Elagolix 200 MG. Philadelphia also shows promise with 6 active trials investigating approaches like femaSeed localized directional insemination and programmed cycles. Other notable cities include Oklahoma City with 5 active trials studying similar techniques, and San Francisco with its own set of 5 ongoing investigations into promising methods like ZP bound sperm selection oocyte cohort. These dedicated research efforts offer hope for individuals struggling with infertility by advancing our understanding and expanding treatment options.
Which are the top treatments for infertility being explored in clinical trials?
Exciting advancements in infertility treatments are taking place through various clinical trials. Uterine transplant, a groundbreaking procedure, is currently being explored in three active trials dedicated to addressing infertility. Its first listing dates back to 2015 and it has been involved in four all-time infertility trials. Another innovative approach is sperm sorting, which has shown promise with one ongoing trial since its introduction in 2013. Additionally, automated sperm selection software offers a potential solution and is currently under investigation in one active trial after being listed for the first time in 2021. These cutting-edge developments hold great potential for individuals struggling with infertility as researchers strive to expand treatment options and bring hope into their lives.
What are the most recent clinical trials for infertility?
Recent clinical trials offer promising advancements in the field of infertility, providing hope for individuals struggling to conceive. One notable trial examines the efficacy of kisspeptin and GnRH in addressing infertility concerns. Another significant study focuses on uterus transplant recipients, aiming to expand our understanding of this innovative procedure's impact on fertility. Additionally, researchers are investigating the potential benefits of green tea extract as a treatment option for infertility. Furthermore, Endometrin 100 mg three times per day (TID) is being studied for its effectiveness in enhancing fertility outcomes. These ongoing trials demonstrate the relentless pursuit towards finding effective solutions for couples facing challenges with conception.
What infertility clinical trials were recently completed?
Recently, several significant clinical trials have concluded, contributing valuable insights into the field of infertility treatment. In July 2022, American Genomics conducted a trial on AG-920 to address this pressing issue. Furthermore, Stanford University completed a trial in August 2017 exploring Uterine ERA and microbiome testing. Finally, Letrozole was investigated by Weill Medical College of Cornell University in November 2009 as a potential therapy for infertility. These studies exemplify the ongoing efforts to advance medical knowledge and provide hope for couples struggling with infertility.